About: Developments of Riboswitches and Toehold Switches for Molecular Detection

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About: Developments of Riboswitches and Toehold Switches for Molecular Detection—Biosensing and Molecular Diagnostics Goto Sponge NotDistinct Permalink

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Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Developments of Riboswitches and Toehold Switches for Molecular Detection—Biosensing and Molecular Diagnostics
Creator	Lee, Eun Le, Quynh Pham, Ngoc Chau, Trung Hoang, Dung Hoang, Tin Mai, Anh Thi, Hoa
topic	covid:7310f25a90a9e1cf770958793a6ab35120cf0e78#this
source	PMC
abstract	Riboswitches and toehold switches are considered to have potential for implementation in various fields, i.e., biosensing, metabolic engineering, and molecular diagnostics. The specific binding, programmability, and manipulability of these RNA-based molecules enable their intensive deployments in molecular detection as biosensors for regulating gene expressions, tracking metabolites, or detecting RNA sequences of pathogenic microorganisms. In this review, we will focus on the development of riboswitches and toehold switches in biosensing and molecular diagnostics. This review introduces the operating principles and the notable design features of riboswitches as well as toehold switches. Moreover, we will describe the advances and future directions of riboswitches and toehold switches in biosensing and molecular diagnostics.
has issue date	2020-04-30(xsd:dateTime)
bibo:doi	10.3390/ijms21093192
bibo:pmid	32366036
has license	cc-by
sha1sum (hex)	7310f25a90a9e1cf770958793a6ab35120cf0e78
schema:url	https://doi.org/10.3390/ijms21093192
resource representing a document's title	Developments of Riboswitches and Toehold Switches for Molecular Detection—Biosensing and Molecular Diagnostics
has PubMed Central identifier	PMC7247568
has PubMed identifier	32366036
schema:publication	Int J Mol Sci
resource representing a document's body	covid:7310f25a90a9e1cf770958793a6ab35120cf0e78#body_text
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