About: An Experimental Model for Myocarditis and Congestive Heart Failure after Rabbit Coronavirus Infection

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	An Experimental Model for Myocarditis and Congestive Heart Failure after Rabbit Coronavirus Infection
Creator	Baric, Ralph Small, J Alexander, Lorraine Geratz, Joachim Edwards, Suzanne
Source	Medline; PMC
abstract	In a model for virus-induced myocarditis and congestive heart failure, rabbit coronavirus infection was divided into acute (days 2–5) and subacute (days 6–12) phases on the basis of day of death and pathologic findings. During the acute phase, the principal histologic lesions were degeneration and necrosis of myocytes, myocytolysis, interstitial edema, and hemorrhage. The severity of these changes increased in the subacute phase. Pleural effusion and congestion of the lungs and liver were also present at this time. Myocarditis was detected by day 9 and peaked by day 12. Heart weights and heart weight-to-body weight ratios were increased, and dilation of the right ventricular cavity became prominent early in infection and persisted. In contrast, dilation of the left ventricle occurred late in the subacute stage. Virus was isolated from infected hearts between days 2 and 12. These data suggest that rabbit coronavirus infection progresses to myocarditis and congestive heart failure.
has issue date	1992-01-01(xsd:dateTime)
bibo:doi	10.1093/infdis/165.1.134
bibo:pmid	1309370
has license	no-cc
sha1sum (hex)	73d32a4379d23bc4daa990f811d67a03fbfd9b54
schema:url	https://doi.org/10.1093/infdis/165.1.134
resource representing a document's title	An Experimental Model for Myocarditis and Congestive Heart Failure after Rabbit Coronavirus Infection
has PubMed Central identifier	PMC7202395
has PubMed identifier	1309370
schema:publication	J Infect Dis
resource representing a document's body	covid:73d32a4379d23bc4daa990f811d67a03fbfd9b54#body_text
is schema:about of	named entity 'EARLY' named entity 'HEMORRHAGE' named entity 'LESIONS' named entity 'ACUTE' named entity 'PROGRESSES' named entity 'PROMINENT' named entity 'INCREASED' named entity 'ACUTE PHASE' named entity 'DEGENERATION AND NECROSIS' named entity 'DAY' named entity 'INTERSTITIAL EDEMA' named entity 'CONTRAST' named entity 'THE LUNGS' named entity 'MYOCYTES' named entity 'BODY WEIGHT' named entity 'THESE' covid:arg/73d32a4379d23bc4daa990f811d67a03fbfd9b54 named entity 'coronavirus infection' named entity 'myocytes' named entity 'liver' named entity 'coronavirus infection' named entity 'myocarditis' named entity 'infection' named entity 'pleural effusion' named entity 'infection' named entity 'heart disease' named entity 'subacute' named entity 'virus' named entity 'central veins' named entity 'hemorrhage' named entity 'spleen' named entity 'reovirus' named entity 'heart failure' named entity 'paramyxoviruses' named entity 'heart muscle' named entity 'myocarditis' named entity 'parvovirus' named entity 'coagulative necrosis' named entity 'heart disease' named entity 'heart failure' named entity 'pulmonary edema' named entity 'myocarditis' named entity 'virus infection' named entity 'congestive heart failure' named entity 'subacute' named entity 'subacute' named entity 'pulmonary edema' named entity 'infection' named entity 'acute phase' named entity 'pathogen' named entity 'infection' named entity 'virus' named entity 'heart tissue' named entity 'infection' named entity 'congestion of the lungs' named entity 'hepatic' named entity 'Eppendorf' named entity 'hemorrhage' named entity 'Fisher Scientific' named entity 'myocytes' named entity 'Virus' named entity 'virus' named entity 'picornaviruses' named entity 'etiologic agent' named entity 'body weight' named entity 'infection' named entity 'myocyte' named entity 'left ventricular' named entity 'pulmonary edema' named entity 'pleural effusion' named entity 'myocarditis' named entity 'model systems' named entity 'morphologically' named entity 'encephalomyocarditis virus' named entity 'spleen' named entity 'intercellular spaces' named entity 'myocytes'

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