About: Etiopathogenesis and Pathophysiology of Malaria

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Etiopathogenesis and Pathophysiology of Malaria
Creator	Basilico, Nicoletta Alessandro, Sarah Giribaldi, Giuliana Prato, Mauro
Source	PMC
abstract	Malaria is a parasitic disease caused by Plasmodium protozoan parasites and transmitted by Anopheles mosquitoes. The disease is diffused in tropical areas, where it is associated with high morbidity and mortality. P. falciparum is the most dangerous species, mainly affecting young children. The parasite cycle occurs both in humans (asexual stages) and in mosquitoes (sexual stages). In humans, Plasmodium grows and multiplies within red blood cells using hemoglobin as essential source of nutrients and energy. However, this process generates toxic heme that the parasite aggregates into an insoluble inert biocrystal called hemozoin. This molecule sequesters in various organs (liver, spleen, and brain), potentially contributing to the development of malaria immunopathogenesis. Uncomplicated falciparum malaria clinical frame ranges from asymptomatic infection to classic symptoms such as fever, chills, sweating, headache, and muscle aches. However, malaria can also evolve into severe life-threatening complications, including cerebral malaria, severe anemia, respiratory distress, and acute renal failure.
has issue date	2014-09-22(xsd:dateTime)
bibo:doi	10.1007/978-3-319-09432-8_1
has license	no-cc
sha1sum (hex)	73df8d0312d8ba7d94b32deb2b794d507c917d61
schema:url	https://doi.org/10.1007/978-3-319-09432-8_1
resource representing a document's title	Etiopathogenesis and Pathophysiology of Malaria
has PubMed Central identifier	PMC7123976
schema:publication	Human and Mosquito Lysozymes
resource representing a document's body	covid:73df8d0312d8ba7d94b32deb2b794d507c917d61#body_text
is schema:about of	named entity 'declined' named entity 'World Health Organization (WHO)' named entity 'billion' named entity 'According' named entity 'risk' named entity 'LIVES' named entity 'CASES' named entity 'REMAINS' named entity 'WORLDWIDE' named entity 'CASE' named entity 'ALARMING' named entity 'PLASMODIUM FALCIPARUM' named entity 'ABSOLUTE' named entity 'AT RISK' named entity 'LOW RISK' named entity 'LIKELY' named entity 'ESTIMATES' named entity 'RISK OF' named entity 'consequence' named entity 'During' named entity 'global eradication' named entity 'population' named entity 'program' named entity 'period' named entity 'WHO' named entity 'mortality rates' named entity 'World Health Organization' named entity 'World Health Organization' named entity 'developing countries' named entity 'Etiopathogenesis' named entity 'Malaria' named entity 'phagocytes' named entity 'anemic' named entity 'pathogenesis' named entity 'schizont' named entity 'cytoplasm' named entity 'malaria' named entity 'antigenic variation' named entity 'respiratory distress' named entity 'erythrocytes' named entity 'merozoites' named entity 'respiratory distress' named entity 'merozoites' named entity 'liver' named entity 'IL-8' named entity 'asymptomatic infections' named entity 'vacuoles' named entity 'trophozoite' named entity 'high temperature' named entity '1.2' named entity 'parasite' named entity 'renal dysfunction' named entity 'P. falciparum' named entity 'gametogenesis' named entity 'merozoites' named entity 'anemic' named entity 'vector species' named entity 'RBC' named entity 'parasite' named entity 'dyserythropoiesis' named entity 'mosquito' named entity 'erythrocyte' named entity 'parasites' named entity 'polymer' named entity 'trophozoite' named entity 'neurological' named entity 'blood stream' named entity 'Dormer' named entity 'malaria' named entity 'Nobel Prize' named entity 'merozoite' named entity 'dendritic cells' named entity 'liver' named entity 'parasites' named entity 'blood vessel' named entity 'endemic areas' named entity 'malaria' named entity 'P. falciparum' named entity 'cyst' named entity 'mosquito'

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