About: The Interplay of Viral and Host Factors in Chikungunya Virus Infection: Targets for Antiviral Strategies

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About: The Interplay of Viral and Host Factors in Chikungunya Virus Infection: Targets for Antiviral Strategies Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	The Interplay of Viral and Host Factors in Chikungunya Virus Infection: Targets for Antiviral Strategies
Creator	Chu, Hann Jang, Justin Wong, Kai
topic	covid:756448c2d7dda1e89c0ea4acf6ccd5e2ee02517e#this
Source	Medline; PMC
abstract	Chikungunya virus (CHIKV) has re-emerged as one of the many medically important arboviruses that have spread rampantly across the world in the past decade. Infected patients come down with acute fever and rashes, and a portion of them suffer from both acute and chronic arthralgia. Currently, there are no targeted therapeutics against this debilitating virus. One approach to develop potential therapeutics is by understanding the viral-host interactions. However, to date, there has been limited research undertaken in this area. In this review, we attempt to briefly describe and update the functions of the different CHIKV proteins and their respective interacting host partners. In addition, we also survey the literature for other reported host factors and pathways involved during CHIKV infection. There is a pressing need for an in-depth understanding of the interaction between the host environment and CHIKV in order to generate potential therapeutics.
has issue date	2018-05-30(xsd:dateTime)
bibo:doi	10.3390/v10060294
bibo:pmid	29849008
has license	cc-by
sha1sum (hex)	756448c2d7dda1e89c0ea4acf6ccd5e2ee02517e
schema:url	https://doi.org/10.3390/v10060294
resource representing a document's title	The Interplay of Viral and Host Factors in Chikungunya Virus Infection: Targets for Antiviral Strategies
has PubMed Central identifier	PMC6024654
has PubMed identifier	29849008
schema:publication	Viruses
resource representing a document's body	covid:756448c2d7dda1e89c0ea4acf6ccd5e2ee02517e#body_text
is http://vocab.deri.ie/void#inDataset of	proxy:http/ns.inria.fr/covid19/756448c2d7dda1e89c0ea4acf6ccd5e2ee02517e
is schema:about of	named entity 'VIRAL-' named entity 'VIRUSES' named entity 'VIRUS' covid:arg/756448c2d7dda1e89c0ea4acf6ccd5e2ee02517e named entity 'STRATEGIES' named entity 'ATTEMPT' named entity 'CHIKUNGUNYA VIRUS INFECTION' named entity 'ANTIVIRAL' named entity 'UNDERSTANDING' named entity 'DECADE' named entity 'DESCRIBE' named entity 'THEIR' named entity 'IS A' named entity 'FEVER' named entity 'DIFFERENT' named entity 'COME' named entity 'ACROSS' named entity 'LIMITED' named entity 'THERAPEUTICS' named entity 'CHIKV INFECTION' named entity 'HOST' named entity 'AREA' named entity 'SPREAD' named entity 'IN THE PAST' named entity 'LITERATURE' named entity 'TARGETS' named entity 'APPROACH' named entity 'PRESSING' named entity 'TARGETED' named entity 'ORDER' named entity 'PORTION' named entity 'INTERACTION' named entity 'ACUTE' named entity 'SURVEY' named entity 'INTERACTING' named entity 'ADDITION' named entity 'FUNCTIONS' named entity 'ARTHRALGIA' named entity 'HAVE' named entity 'REPORTED' named entity 'INVOLVED' named entity 'RASHES' named entity 'SUFFER' named entity 'DEPTH' named entity 'PROTEINS' named entity 'POTENTIAL' named entity 'NEED FOR' named entity 'INFECTED' named entity 'CHRONIC' named entity 'PATHWAYS' named entity 'REVIEW' named entity 'RESEARCH' named entity 'CURRENTLY' named entity 'WORLD' named entity 'IMPORTANT' named entity 'ONE OF' named entity 'INTERACTIONS' named entity 'HOST' named entity 'UPDATE' named entity 'GENERATE' named entity 'DATE' named entity 'PARTNERS' named entity 'PATIENTS' named entity 'VIRAL AND' named entity 'ARBOVIRUSES' named entity 'CHIKUNGUNYA VIRUS' named entity 'ENVIRONMENT' named entity 'targeted therapeutics' named entity 'CHIKV' named entity 'arthralgia' named entity 'Infection' named entity 'viruses' named entity 'viral protein' named entity 'AXL receptor tyrosine kinase' named entity 'TGF-β1' named entity 'RSV' named entity 'tyrosine kinase'

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