About: Molecular evolution and multilocus sequence typing of 145 strains of SARS-CoV

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About: Molecular evolution and multilocus sequence typing of 145 strains of SARS-CoV Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Molecular evolution and multilocus sequence typing of 145 strains of SARS-CoV
Creator	Bao, Qi-Yu Wang, Zhi-Gang Zhang, Yan-Jun Luo, Yun Li, Lan-Juan Shang, Lei Cheng, Su-Yun Cong, Li-Ming Feng, Ming-Guang Ru, Miao-Gui Wang, Zan-Xin Zheng, Zhi-Hua
Source	Elsevier; Medline; PMC
abstract	In this study, we have identified 876 polymorphism sites in 145 complete or partial genomes of SARS-CoV available in the NCBI GenBank. One hundred and seventy-four of these sites existed in two or more SARS-CoV genome sequences. According to the sequence polymorphism, all SARS-CoVs can be divided into three groups: (I) group 1, animal-origin viruses (such as SARS-CoV SZ1, SZ3, SZ13 and SZ16); (II) group 2, all viruses with clinical origin during first epidemic; and (III) group 3, SARS-CoV GD03T0013. According to 10 special loci, group 2 again can be divided into genotypes C and T, which can be further divided into sub-genotypes C1–C4 and T1–T4. Positive Darwinian selections were identified between any pair of these three groups. Genotype C gives neutral selection. Genotype T, however, shows negative selection. By comparing the death rates of SARS patients in the different regions, it was found that the death rate caused by the viruses of the genotype C was lower than that of the genotype T. SARS-CoVs might originate from an unknown ancestor.
has issue date	2005-09-12(xsd:dateTime)
bibo:doi	10.1016/j.febslet.2005.07.075
bibo:pmid	16112670
has license	no-cc
sha1sum (hex)	760cc4d3a4770698be59f66713d930d5581eddc7
schema:url	https://doi.org/10.1016/j.febslet.2005.07.075
resource representing a document's title	Molecular evolution and multilocus sequence typing of 145 strains of SARS-CoV
has PubMed Central identifier	PMC7118731
has PubMed identifier	16112670
schema:publication	FEBS Lett
resource representing a document's body	covid:760cc4d3a4770698be59f66713d930d5581eddc7#body_text
is schema:about of	named entity 'STRAINS' named entity 'divided' named entity 'SARS-CoV' named entity 'origin' named entity 'multilocus sequence typing' named entity 'COVS' named entity 'GROUPS' named entity 'PATIENTS' named entity 'CLINICAL' named entity 'ANCESTOR' named entity 'ONE HUNDRED' named entity 'DEATH RATES' named entity 'DIFFERENT' named entity 'SEQUENCES' named entity 'PARTIAL' named entity 'LOCI' named entity 'DIVIDED' named entity 'HAVE' named entity 'ACCORDING' named entity 'EPIDEMIC' named entity 'GENOTYPE' named entity 'NEUTRAL' named entity 'IDENTIFIED' named entity 'MULTILOCUS SEQUENCE TYPING' named entity 'MOLECULAR EVOLUTION' named entity 'SARS-COV' named entity 'GROUP 1' named entity '145' named entity 'SELECTION' named entity 'COMPARING' named entity '876' named entity 'SARS' named entity 'SARS-COV' named entity 'SPECIAL' named entity '579' named entity 'GROUP 3' named entity 'STUDY' named entity 'UNKNOWN' named entity 'NEGATIVE SELECTION' named entity 'DEATH RATE' named entity 'VIRUSES' named entity '28I' named entity 'LETTERS' named entity 'PAIR' named entity 'COMPLETE' named entity '29875' named entity 'SITES' named entity 'THESE' named entity 'ANIMAL' named entity 'TWO OR MORE' named entity 'CAUSED BY' named entity '4928' named entity 'NCBI' named entity 'GENOMES' named entity 'ORIGIN' named entity 'GENOTYPES' named entity 'J 3' named entity 'GROUP 2' named entity 'GENBANK' named entity 'REGIONS' named entity '145' named entity 'POSITIVE' named entity 'LOWER' named entity 'AVAILABLE' named entity 'FOUND' named entity 'POLYMORPHISM' named entity 'SEQUENCE' covid:arg/760cc4d3a4770698be59f66713d930d5581eddc7 named entity 'SARS-CoV' named entity 'divided'

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