About: Genomic characterization of two novel polyomaviruses in Brazilian insectivorous bats

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About: Genomic characterization of two novel polyomaviruses in Brazilian insectivorous bats Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Genomic characterization of two novel polyomaviruses in Brazilian insectivorous bats
Creator	Cibulski, Paulo Esmaile, Francisco Franco, Ana Lima, Sales Roehe, Paulo Samuel, • André, • Witt, Alberto
Source	Medline; PMC
abstract	Two novel genomes comprising ≈4.9 kb were identified by next-generation sequencing from pooled organs of Tadarida brasiliensis bats. The overall nucleotide sequence identities between the viral genomes characterized here were less than 80 % in comparison to other polyomaviruses (PyVs), members of the family Polyomaviridae. The new genomes display the archetypal organization of PyVs, which includes open reading frames for the regulatory proteins small T antigen (STAg) and large T antigen (LTAg), as well as capsid proteins VP1, VP2 and VP3. In addition, an alternate ORF was identified in the early genome region that is conserved in a large monophyletic group of polyomaviruses. Phylogenetic analysis showed similar clustering with group of PyVs detected in Otomops and Chaerephon bats and some species of monkeys. In this study, the genomes of two novel PyVs were detected in bats of a single species, demonstrating that these mammals can harbor genetically diverse polyomaviruses.
has issue date	2015-05-12(xsd:dateTime)
bibo:doi	10.1007/s00705-015-2447-6
bibo:pmid	25963124
has license	no-cc
sha1sum (hex)	797bae7ffe149daf5b05e9cc542d51027b7fae78
schema:url	https://doi.org/10.1007/s00705-015-2447-6
resource representing a document's title	Genomic characterization of two novel polyomaviruses in Brazilian insectivorous bats
has PubMed Central identifier	PMC7086640
has PubMed identifier	25963124
schema:publication	Arch Virol
resource representing a document's body	covid:797bae7ffe149daf5b05e9cc542d51027b7fae78#body_text
is schema:about of	named entity 'polyomaviruses' named entity 'COMPARISON' named entity 'OPEN READING FRAMES' named entity 'MONOPHYLETIC' named entity 'DISPLAY' named entity 'VP3' named entity 'IDENTIFIED' named entity 'REGION' named entity 'GENOMES' named entity 'GENOME' named entity 'INCLUDES' named entity 'EARLY' named entity 'GENOMIC' named entity 'ORF' named entity 'NOVEL' named entity 'CONSERVED' named entity 'CAPSID PROTEINS' named entity 'CLUSTERING' named entity 'VP1' named entity 'CHARACTERIZATION' named entity 'BRAZILIAN' named entity 'POLYOMAVIRUSES' named entity 'LESS THAN' named entity 'NEW' named entity 'OTOMOPS' named entity 'ORGANIZATION' named entity 'MAMMALS' named entity 'BATS' named entity 'MONKEYS' named entity 'VP2' named entity 'VIRAL' named entity 'SIMILAR' named entity 'THESE' named entity 'DIVERSE' named entity 'CHARACTERIZED' named entity 'BATS' named entity 'ALTERNATE' named entity 'LARGE T ANTIGEN' named entity 'CHAEREPHON' named entity 'SMALL T ANTIGEN' named entity 'NEXT-GENERATION SEQUENCING' named entity 'OVERALL' named entity 'NUCLEOTIDE SEQUENCE' named entity 'MEMBERS' named entity 'NOVEL' named entity 'FAMILY POLYOMAVIRIDAE' named entity 'ORGANS' named entity 'STUDY' named entity 'SINGLE' named entity 'ADDITION' named entity 'TADARIDA BRASILIENSIS' named entity 'LARGE' named entity 'DETECTED' named entity 'POOLED' named entity 'POLYOMAVIRUSES' named entity 'GROUP' named entity 'HERE' named entity 'IDENTITIES' named entity 'SPECIES' named entity 'REGULATORY PROTEINS' named entity 'IDENTIFIED BY' named entity 'HARBOR' named entity 'PHYLOGENETIC ANALYSIS' covid:arg/797bae7ffe149daf5b05e9cc542d51027b7fae78 named entity 'genomes' named entity 'antigen' named entity 'Polyomaviridae' named entity 'family' named entity 'detected' named entity 'addition' named entity 'capsid proteins' named entity 'ORF' named entity 'regulatory proteins' named entity 'large T antigen'

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