About: Middle East Respiratory Syndrome Coronavirus: A Case-Control Study of Hospitalized Patients

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Middle East Respiratory Syndrome Coronavirus: A Case-Control Study of Hospitalized Patients
Creator	Memish, Ziad Hinedi, Kareem Al-Tawfiq, Jaffar Ghandour, Jihad Khairalla, Hanan Musleh, Samir Ujayli, Alaa
source	Medline; PMC
abstract	Background. There is a paucity of data regarding the differentiating characteristics of patients with laboratory-confirmed and those negative for Middle East respiratory syndrome coronavirus (MERS-CoV). Methods. This is a hospital-based case-control study comparing MERS-CoV–positive patients (cases) with MERS-CoV–negative controls. Results. A total of 17 case patients and 82 controls with a mean age of 60.7 years and 57 years, respectively (P = .553), were included. No statistical differences were observed in relation to sex, the presence of a fever or cough, and the presence of a single or multilobar infiltrate on chest radiography. The case patients were more likely to be overweight than the control group (mean body mass index, 32 vs 27.8; P = .035), to have diabetes mellitus (87% vs 47%; odds ratio [OR], 7.24; P = .015), and to have end-stage renal disease (33% vs 7%; OR, 7; P = .012). At the time of admission, tachypnea (27% vs 60%; OR, 0.24; P = .031) and respiratory distress (15% vs 51%; OR, 0.15; P = .012) were less frequent among case patients. MERS-CoV patients were more likely to have a normal white blood cell count than the control group (82% vs 52%; OR, 4.33; P = .029). Admission chest radiography with interstitial infiltrates was more frequent in case patients than in controls (67% vs 20%; OR, 8.13; P = .001). Case patients were more likely to be admitted to the intensive care unit (53% vs 20%; OR, 4.65; P = .025) and to have a high mortality rate (76% vs 15%; OR, 18.96; P < .001). Conclusions. Few clinical predictors could enhance the ability to predict which patients with pneumonia would have MERS-CoV. However, further prospective analysis and matched case-control studies may shed light on other predictors of infection.
has issue date	2014-07-15(xsd:dateTime)
bibo:doi	10.1093/cid/ciu226
bibo:pmid	24723278
has license	no-cc
sha1sum (hex)	79fd3b47ebeeace82c2f7709b0e66ae42e63c7d4
schema:url	https://doi.org/10.1093/cid/ciu226
resource representing a document's title	Middle East Respiratory Syndrome Coronavirus: A Case-Control Study of Hospitalized Patients
has PubMed Central identifier	PMC7108071
has PubMed identifier	24723278
schema:publication	Clin Infect Dis
resource representing a document's body	covid:79fd3b47ebeeace82c2f7709b0e66ae42e63c7d4#body_text
is schema:about of	named entity 'MIDDLE EAST RESPIRATORY SYNDROME CORONAVIRUS' named entity 'MIDDLE EAST RESPIRATORY SYNDROME CORONAVIRUS' named entity 'DATA' named entity 'DIFFERENTIATING' named entity 'CASE-CONTROL STUDY' named entity 'HOSPITALIZED PATIENTS' named entity 'BACKGROUND' named entity 'NEGATIVE' named entity 'CHARACTERISTICS' named entity 'PATIENTS' named entity 'IS A' covid:arg/79fd3b47ebeeace82c2f7709b0e66ae42e63c7d4 named entity 'patients' named entity 'There' named entity 'hemodialysis' named entity 'myalgia' named entity 'infection' named entity 'gastrointestinal symptoms' named entity 'mortality rate' named entity 'pneumonia' named entity 'aspirates' named entity 'risk factors' named entity 'MERS-CoV' named entity 'CAP' named entity 'chest radiography' named entity 'vomiting' named entity 'demographic' named entity 'nasopharyngeal swabs' named entity 'SARS' named entity 'fulminant infections' named entity 'fever' named entity 'body mass index' named entity 'bivariate analysis' named entity 'clinical characteristics' named entity 'MERS-CoV' named entity 'infection' named entity 'clinical presentation' named entity 'control group' named entity 'CT scan' named entity 'electronic medical record' named entity 'ARDS' named entity 'MERS-CoV' named entity 'Asymptomatic' named entity 'statistical significance' named entity 'medical care' named entity 'cardiac disease' named entity 'MERS-CoV' named entity 'infection' named entity 'diabetes mellitus' named entity 'mortality rate' named entity 'vomiting' named entity '21%' named entity 'cardiomegaly' named entity 'fatality rate' named entity 'cardiac disease' named entity 'gene' named entity 'epidemiology' named entity 'triaging' named entity 'reverse-transcription polymerase chain reaction' named entity 'SPSS' named entity 'MERS-CoV' named entity 'Bivariate analysis' named entity 'MERS-CoV' named entity 'MERS-CoV' named entity 'myalgia' named entity 'acute pneumonia' named entity 'symptom' named entity 'MERS-CoV' named entity 'MERS-CoV' named entity 'Male predominance' named entity 'Statistical analysis' named entity 'chest radiography' named entity 'chest radiography' named entity 'MERS-CoV' named entity 'ribavirin'

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