About: Virus-like particles: The new frontier of vaccines for animal viral infections

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About: Virus-like particles: The new frontier of vaccines for animal viral infections Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Virus-like particles: The new frontier of vaccines for animal viral infections
Creator	Bárcena, Juan Crisci, Elisa Montoya, María
Source	Elsevier; Medline; PMC
abstract	Vaccination continues to be the main approach to protect animals from infectious diseases. Until recently, all licensed vaccines were developed using conventional technologies. Subunit vaccines are, however, gaining attention from researchers in the field of veterinary vaccinology, and among these, virus-like particles (VLPs) represent one of the most appealing approaches. VLPs are robust protein cages in the nanometer range that mimic the overall structure of the native virions but lack the viral genome. They are often antigenically indistinguishable from the virus from which they were derived and present important advantages in terms of safety. VLPs can stimulate strong humoral and cellular immune responses and have been shown to exhibit self-adjuvanting abilities. In addition to their suitability as a vaccine for the homologous virus from which they are derived, VLPs can also be used as vectors for the multimeric presentation of foreign antigens. VLPs have therefore shown dramatic effectiveness as candidate vaccines. Here, we review the current status of VLPs as a vaccine technology in the veterinary field, and discuss the potential advantages and challenges of this technology.
has issue date	2012-08-15(xsd:dateTime)
bibo:doi	10.1016/j.vetimm.2012.04.026
bibo:pmid	22705417
has license	no-cc
sha1sum (hex)	7a1da051f66f6951fbd91f49609ed1fa884321f9
schema:url	https://doi.org/10.1016/j.vetimm.2012.04.026
resource representing a document's title	Virus-like particles: The new frontier of vaccines for animal viral infections
has PubMed Central identifier	PMC7112581
has PubMed identifier	22705417
schema:publication	Vet Immunol Immunopathol
resource representing a document's body	covid:7a1da051f66f6951fbd91f49609ed1fa884321f9#body_text
is schema:about of	named entity 'antigens' named entity 'attention' named entity 'mimic' named entity 'presentation' named entity 'Vaccination' named entity 'effectiveness' named entity 'candidate' named entity 'animal' named entity 'REVIEW' named entity 'PRESENTATION' named entity 'VACCINES' named entity 'USED' named entity 'IMMUNE RESPONSES' named entity 'ONE OF' named entity 'CANDIDATE' named entity 'USING' named entity 'TERMS' named entity 'OVERALL' named entity 'EFFECTIVENESS' named entity 'STATUS' named entity 'TECHNOLOGIES' named entity 'STRONG' named entity 'FOREIGN' named entity 'CONVENTIONAL' named entity 'IN THE FIELD' named entity 'FIELD' named entity 'GAINING' named entity 'RECENTLY' named entity 'BUT' named entity 'THEIR' named entity 'HERE' named entity 'LICENSED' named entity 'CELLULAR' named entity 'VETERINARY' named entity 'HOMOLOGOUS' named entity 'IMPORTANT' named entity 'THESE' named entity 'INFECTIOUS DISEASES' named entity 'MIMIC' named entity 'LACK' named entity 'VIRAL INFECTIONS' named entity 'VIRAL GENOME' named entity 'ABILITIES' named entity 'VIRUS-LIKE PARTICLES' named entity 'VIRUS-LIKE PARTICLES' named entity 'VACCINOLOGY' named entity 'NANOMETER' named entity 'NATIVE' named entity 'ROBUST' named entity 'VECTORS' named entity 'ANIMAL' named entity 'VIRUS' named entity 'EXHIBIT' named entity 'ANIMALS' named entity 'CAGES' named entity 'NEW' named entity 'VLPS' named entity 'REPRESENT' named entity 'STRUCTURE' named entity 'MAIN' named entity 'HAVE' named entity 'APPROACHES' named entity 'APPEALING' named entity 'ATTENTION' named entity 'CURRENT' named entity 'PROTEIN ' named entity 'PRESENT' named entity 'VIRIONS' named entity 'VACCINE' named entity 'SAFETY' named entity 'POTENTIAL' named entity 'ANTIGENS' named entity 'VACCINATION' named entity 'SUBUNIT VACCINES' named entity 'STIMULATE' named entity 'RANGE' named entity 'APPROACH' named entity 'SELF' named entity 'DISCUSS'

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