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About:
Estimate of the development of the epidemic reproduction number Rt from Coronavirus SARS-CoV-2 case data and implications for political measures based on prognostics
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wasabi.inria.fr
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Academic Article
research paper
schema:ScholarlyArticle
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type
Academic Article
research paper
schema:ScholarlyArticle
isDefinedBy
Covid-on-the-Web dataset
has title
Estimate of the development of the epidemic reproduction number Rt from Coronavirus SARS-CoV-2 case data and implications for political measures based on prognostics
Creator
Arnab, §
Bandyopadhyay,
Berit,
Binder,
Khailaie,
Lange,
Marta, §
Mascheroni,
Meyer-Hermann, Sebastian
Michael, #
Patrizio,
Sahamoddin, Mitra
Schips,
Tanmay,
Vanella, Pietro
Source
MedRxiv
abstract
The novel Coronavirus SARS-CoV-2 (CoV) has induced a world-wide pandemic and subsequent non-pharmaceutical interventions (NPI) in order to control the spreading of the virus. NPIs are considered to be critical in order to at least delay the peak number of infected individuals and to prevent the health care system becoming overwhelmed by the number of patients to treat in hospitals or in intensive care units (ICUs). However, there is also increasing concern that the NPIs in place would increase mortality because of other diseases, increase the frequency of suicide and increase the risk of an economic recession with unforeseeable implications. It is therefore instrumental to evaluate the necessity of NPIs and to monitor the progress of containment of the virus spreading. We used a data-driven estimation of the evolution of the reproduction number for viral spreading in Germany as well as in all its federal states. Based on an extended infection-epidemic model, parameterized with data from the Robert Koch-Institute and, alternatively, with parameters stemming from a fit to the initial phase of CoV spreading in different regions of Italy, we consistently found that the reproduction number was turned down to a range near 1 in all federal states. We used the latest reproduction number as a starting point for the simulation of epidemic progression and varied the reproduction number, mimicking either release or strengthening of NPIs. Germany is currently, April 3rd, 2020, at the border line of a reproduction number between the scenarios of major immunisation of the population or eradication of the virus. We strongly recommend to keep all NPIs in place and suggest to even strengthen the measures in order to accelerate reaching the state of full control, thus, also limiting collateral damage of the NPIs in time.
has issue date
2020-04-07
(
xsd:dateTime
)
bibo:doi
10.1101/2020.04.04.20053637
has license
medrxiv
sha1sum (hex)
7c3c810250221b9947a2848a87a2b9126c545939
schema:url
https://doi.org/10.1101/2020.04.04.20053637
resource representing a document's title
Estimate of the development of the epidemic reproduction number Rt from Coronavirus SARS-CoV-2 case data and implications for political measures based on prognostics
resource representing a document's body
covid:7c3c810250221b9947a2848a87a2b9126c545939#body_text
is
schema:about
of
named entity 'ESTIMATE'
named entity 'induced'
named entity 'patients'
named entity 'Coronavirus'
named entity 'CORONAVIRUS SARS'
named entity 'BASED'
named entity 'EPIDEMIC'
named entity 'SARS-COV-2'
named entity 'SPREADING'
named entity 'INTERVENTIONS'
named entity 'DISEASES'
named entity 'CONTAINMENT'
named entity 'HOSPITALS'
named entity 'HEALTH CARE SYSTEM'
named entity 'EVALUATE'
named entity 'TO CONTROL'
named entity 'INDUCED'
named entity 'DELAY'
named entity 'CASE'
named entity 'NOVEL CORONAVIRUS'
named entity 'THE PEAK'
named entity 'RISK OF'
named entity 'INSTRUMENTAL'
named entity 'MEASURES'
named entity 'DATA'
named entity 'PANDEMIC'
named entity 'NECESSITY'
named entity 'ORDER'
named entity 'INFECTED'
named entity 'CORONAVIRUS SARS'
named entity 'INCREASING'
named entity 'INDIVIDUALS'
named entity 'SUBSEQUENT'
named entity 'PROGRESS'
named entity 'NON-'
named entity 'PHARMACEUTICAL'
named entity 'WIDE'
named entity 'PLACE'
named entity 'INCREASE'
named entity 'INTENSIVE CARE UNITS'
named entity 'WORLD'
named entity 'FREQUENCY'
named entity 'VIRUS'
named entity 'SUICIDE'
named entity 'SARS-COV-2'
named entity 'CONCERN'
named entity 'ECONOMIC RECESSION'
named entity 'DEVELOPMENT'
named entity 'THE NUMBER OF PATIENTS'
named entity 'NUMBER OF'
named entity 'TO PREVENT'
named entity 'CONSIDERED'
named entity 'CRITICAL'
named entity 'REPRODUCTION NUMBER'
named entity 'MORTALITY'
named entity 'MONITOR'
named entity 'TREAT'
covid:arg/7c3c810250221b9947a2848a87a2b9126c545939
named entity 'infected'
named entity 'control'
named entity 'suicide'
named entity 'Estimate'
named entity 'world-wide'
named entity 'suicide'
named entity 'virus'
named entity 'ICUs'
named entity 'pharmaceutical'
named entity 'SARS-CoV-2'
named entity 'mortality'
named entity 'self-isolation'
named entity '4.2'
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