About: A comparison of the susceptibility of three human gut tumour-derived differentiated epithelial cell lines, primary monkey kidney cells and human rhabdomyosarcoma cell line to 66-prototype strains of human enteroviruses

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About: A comparison of the susceptibility of three human gut tumour-derived differentiated epithelial cell lines, primary monkey kidney cells and human rhabdomyosarcoma cell line to 66-prototype strains of human enteroviruses Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	A comparison of the susceptibility of three human gut tumour-derived differentiated epithelial cell lines, primary monkey kidney cells and human rhabdomyosarcoma cell line to 66-prototype strains of human enteroviruses
Creator	Daniel, J Mathan, V Patel, J
Source	Elsevier; Medline; PMC
abstract	Abstract The growth of prototype strains of 31 serotypes of ECHO, 3 polio, 6 Coxsackie B, 24 Coxsackie A and enterovirus serotypes 70 and 71 were tested in parallel in primary monkey kidney cells (PMK), RD cells and three gut tumour-derived differentiated epithelial cell lines (HRT-18 HT-29 in SKCO-1). All 31 serotypes of ECHO viruses grew in HT-29, 27 and SKCO-1, 5 in HRT-18, 29 in PMK and 29 in RD. There was good growth of poliovirus serotypes in all five cell types. Coxsackie B viruses grew well in all the cell lines except RD. Fifteen of the Coxsackie A viruses grew in SKCO-1, 4 in HT-29, 3 in HRT-18 and 7 in RD. Enterovirus serotypes 70 and 71 grew only in RD cells after 3 serial passages. These results showed that 2 of the gut tumour-derived cell lines, HT-29 and SKCO-1 had a markedly wider susceptibility, with comparable or wider sensitivity, for enteroviruses, than PMK and RD. While their use for field isolation from clinical samples is not yet fully established HT-29 and SKCO-1 would appear to be ideal for a variety of laboratory manipulations of the majority of enteroviruses.
has issue date	1985-12-31(xsd:dateTime)
bibo:doi	10.1016/0166-0934(85)90131-4
bibo:pmid	3009511
has license	els-covid
sha1sum (hex)	7cf71f827bd694ce2b77c160dbd43d3d2b2da9a8
schema:url	https://doi.org/10.1016/0166-0934%2885%2990131-4
resource representing a document's title	A comparison of the susceptibility of three human gut tumour-derived differentiated epithelial cell lines, primary monkey kidney cells and human rhabdomyosarcoma cell line to 66-prototype strains of human enteroviruses
has PubMed Central identifier	PMC7119559
has PubMed identifier	3009511
schema:publication	Journal of Virological Methods
resource representing a document's body	covid:7cf71f827bd694ce2b77c160dbd43d3d2b2da9a8#body_text
is schema:about of	named entity 'PRIMARY' named entity 'DIFFERENTIATED' named entity 'cells' named entity 'lines' named entity 'cells' named entity 'enteroviruses' named entity 'HT-29' named entity 'susceptibility' named entity 'HT-29' named entity 'isolation' named entity 'serotypes' named entity 'HUMAN' named entity 'HUMAN' named entity 'SENSITIVITY' named entity 'PMK' named entity 'THEIR' named entity 'STRAINS' named entity 'SCIENCE' named entity 'ECHO' named entity 'DIFFERENTIATED' named entity 'PARALLEL' named entity 'DERIVED' named entity 'ENTEROVIRUS' named entity 'EPITHELIAL CELL' named entity 'EXCEPT' named entity 'COXSACKIE B' named entity 'SAMPLES' named entity 'MONKEY' named entity 'SERIAL' covid:arg/7cf71f827bd694ce2b77c160dbd43d3d2b2da9a8 named entity 'STRAINS' named entity 'KIDNEY' named entity '2C4' named entity 'HT-29' named entity 'KIDNEY' named entity 'SEROTYPES' named entity 'APPEAR' named entity 'FIELD' named entity 'HUMAN' named entity 'TUMOUR' named entity 'ENTEROVIRUSES' named entity 'RHABDOMYOSARCOMA CELL LINE' named entity 'DERIVED' named entity 'SUSCEPTIBILITY' named entity 'GUT' named entity 'MONKEY' named entity 'COMPARISON' named entity 'CELL LINES' named entity 'RESULTS' named entity 'MAJORITY' named entity 'RHABDOMYOSARCOMA CELL LINE' named entity 'CORRESPONDENCE' named entity '166' named entity 'CELLS' named entity 'PRIMARY' named entity 'GROWTH' named entity 'FIFTEEN' named entity 'VIRUSES' named entity 'TESTED' named entity 'DIVISION' named entity 'EPITHELIAL CELL' named entity '1.5' named entity 'MARKEDLY' named entity 'ECHO VIRUSES' named entity 'CELLS' named entity 'IDEAL' named entity 'TUMOUR' named entity 'CELL TYPES' named entity 'CLINICAL' named entity 'THESE' named entity 'SUSCEPTIBILITY' named entity 'CELL LINES' named entity 'ESTABLISHED' named entity 'ISOLATION' named entity 'POLIO' named entity 'PROTOTYPE' named entity 'GOOD' named entity 'GUT' named entity 'THE GUT'

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