About: Cardiac involvement in recovered COVID-19 patients identified by magnetic resonance imaging

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About: Cardiac involvement in recovered COVID-19 patients identified by magnetic resonance imaging Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Cardiac involvement in recovered COVID-19 patients identified by magnetic resonance imaging
Creator	Zhu, Tong Liu, Weiyong Tao, Qian Xia, Liming Zhan, Chenao Huang, Lu Han, Rui Zeng, Hesong Tang, Dazhong Zhao, Peijun
topic	covid:7d273b6786ff09629d5aaf2f3f165d3a074f98c3#this
Source	Elsevier; Medline; PMC
abstract	Abstract Objective To evaluate cardiac involvement in recovered COVID-19 patients using cardiac MRI. Background Myocardial injury caused by COVID-19 was previously reported in hospitalized patients. It is unknown if there is sustained cardiac involvement after patients’ recovery from COVID-19. Methods Twenty-six recovered COVID-19 patients that reported cardiac symptoms and underwent MRI exams were retrospectively included. MRI protocols consisted of conventional sequences (cine, T2WI, LGE), and quantitative mapping sequences (T1, T2, and ECV mapping). Edema ratio and LGE were assessed in post-COVID-19 patients. Cardiac function, native T1/T2, and ECV were quantitatively evaluated and compared with controls. Results Fifteen patients (58%) had abnormal MRI findings on conventional MRI sequences: myocardial edema was found in 14 (54%) patients and LGE was found in 8 (31%) patients. Decreased RV functional parameters including EF, CI, and SV/ BSA were found in patients with positive conventional MRI findings. Using quantitative mapping, global native T1, T2, and ECV were all found to be significantly elevated in patients with positive conventional MRI findings, compared to patients without positive findings and controls (median [IQR], native T1 1271ms [1243-1298] vs 1237ms [1216-1262] vs 1224ms [1217-1245]; mean [SD], T2 42.7ms [3.1] vs 38.1ms [2.4] vs 39.1ms [3.1]; median [IQR], 28.2% [24.8-36.2] vs 24.8% [23.1-25.4] vs 23.7% [22.2-25.2]; p=0.002, p <0.001, and p =0.002, respectively). Conclusions Cardiac involvement was found in a proportion of the recovered COVID-19 patients. MRI manifestation included myocardial edema, fibrosis, and impaired RV function. Attention should be paid to the possible myocardial involvement in recovered COVID-19 patients with cardiac symptoms.
has issue date	2020-05-12(xsd:dateTime)
bibo:doi	10.1016/j.jcmg.2020.05.004
bibo:pmid	32763118
has license	els-covid
sha1sum (hex)	7d273b6786ff09629d5aaf2f3f165d3a074f98c3
schema:url	https://doi.org/10.1016/j.jcmg.2020.05.004
resource representing a document's title	Cardiac involvement in recovered COVID-19 patients identified by magnetic resonance imaging
has PubMed Central identifier	PMC7214335
has PubMed identifier	32763118
schema:publication	JACC Cardiovasc Imaging
resource representing a document's body	covid:7d273b6786ff09629d5aaf2f3f165d3a074f98c3#body_text
is http://vocab.deri.ie/void#inDataset of	https://covidontheweb.inria.fr:4443/about/id/http/ns.inria.fr/covid19/7d273b6786ff09629d5aaf2f3f165d3a074f98c3
is schema:about of	named entity 'compared' named entity 'positive' named entity 'patients' named entity 'evaluated' named entity 'sustained' named entity 'patients' named entity 'LGE' named entity 'IQR' named entity 'Cardiac' named entity 'COVID-19' named entity 'COVID-19' named entity 'identified' named entity 'MRI' named entity 'functional' named entity 'FOV' named entity 'COVID' named entity 'acute respiratory distress syndrome' named entity 'end-diastolic volume' named entity 'morphological' named entity 'cardiac output' named entity 'myocarditis' named entity 'cardiac involvement' named entity 'GraphPad Prism' named entity 'Myocardial' named entity 'quantitatively' named entity 'ratio' named entity 'controls' named entity 'Edema' named entity 'patients' named entity 'patients' named entity 'myocardial' named entity 'Siemens' named entity 'SARS-CoV-2' named entity 'COVID-19' named entity 'observational study' named entity 'infection' named entity 'cardiac involvement' named entity 'swab test' named entity 'normal range' named entity 'ejection fraction' named entity 'post-contrast' named entity 'MRI' named entity 'clinical symptoms' named entity '8.1' named entity 'lesion' named entity 'cine' named entity 'coronavirus disease 2019' named entity 'Abbreviations' named entity 'BSA' named entity 'recovered' named entity 'cardiac MRI' named entity 'MRI' named entity 'MRI sequences' named entity 'reverse transcription' named entity 'ventricle' named entity 'polymerase chain reaction' named entity 'COVID-19' named entity 'extracellular volume' named entity 'gadolinium enhancement' named entity 'cTnI' named entity 'BSA' named entity 'IQR' named entity 'March 2020' named entity 'ACE2' named entity 'normal distribution' named entity 'SARS-CoV-2' named entity 'end-systolic volume' named entity 'edema' named entity 'fibrosis' named entity 'cardiac arrhythmias'

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