About: Patterns of Rift Valley fever virus seropositivity in domestic ruminants in central South Africa four years after a large outbreak

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About: Patterns of Rift Valley fever virus seropositivity in domestic ruminants in central South Africa four years after a large outbreak Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Patterns of Rift Valley fever virus seropositivity in domestic ruminants in central South Africa four years after a large outbreak
Creator	Kemp, Alan Karesh, William Paweska, Janusz Msimang, Veerle Rostal, Melinda Thompson, Peter Avenant, Alida Bagge, Whitney Cordel, Claudia Ngoshe, Yusuf Van Vuren, Jansen
Source	PMC
abstract	Rift Valley fever (RVF) is a mosquito-borne viral zoonosis showing complex epidemiological patterns that are poorly understood in South Africa. Large outbreaks occur in the central interior at long, irregular intervals, most recently in 2010–2011; however, the level of herd immunity of ruminant livestock, a key determinant of outbreaks, is unknown. During 2015–2016 a cross-sectional study on 234 randomly-selected farms investigated the prevalence, patterns of, and factors associated with, antibodies to RVF virus (RVFV) in livestock in an area heavily affected by that outbreak. A RVFV inhibition ELISA was used to screen 977 cattle, 1,549 sheep and 523 goats and information on potential risk factors was collected using a comprehensive questionnaire. The estimated RVFV seroprevalence, adjusted for survey design, was 42.9% in cattle, 28.0% in sheep and 9.3% in goats, showing a high degree of farm-level clustering. Seroprevalence increased with age and was higher on private vs. communal land, on farms with seasonal pans (temporary, shallow wetlands) and perennial rivers and in recently vaccinated animals. Seropositivity amongst unvaccinated animals born after the last outbreak indicates likely viral circulation during the post-epidemic period. The current level of herd immunity in livestock may be insufficient to prevent another large outbreak, should suitable conditions recur.
has issue date	2020-03-26(xsd:dateTime)
bibo:doi	10.1038/s41598-020-62453-6
bibo:pmid	32218486
has license	cc-by
sha1sum (hex)	7e397dc5770446a6d622f56f37354c1d2fdbb5fd
schema:url	https://doi.org/10.1038/s41598-020-62453-6
resource representing a document's title	Patterns of Rift Valley fever virus seropositivity in domestic ruminants in central South Africa four years after a large outbreak
has PubMed Central identifier	PMC7099094
has PubMed identifier	32218486
schema:publication	Sci Rep
resource representing a document's body	covid:7e397dc5770446a6d622f56f37354c1d2fdbb5fd#body_text
is schema:about of	named entity 'sheep' named entity 'investigated' named entity 'Seropositivity' named entity 'farms' named entity 'ruminants' named entity 'POTENTIAL' named entity 'POST' named entity 'LIVESTOCK' named entity 'USING' named entity 'SOUTH AFRICA' named entity 'AREA' named entity 'DEGREE' named entity 'HIGHER' named entity 'DETERMINANT' named entity 'LEVEL' named entity 'EPIDEMIC PERIOD' named entity 'UNDERSTOOD' named entity 'intervals' named entity 'herd immunity' named entity 'livestock' named entity 'prevent' named entity '2011' named entity 'estimated' named entity 'ruminant' named entity 'goats' named entity 'South Africa' named entity 'collected' named entity 'survey design' named entity 'perennial' named entity 'epidemic' named entity 'survey design' named entity 'cross-sectional study' named entity 'Seropositivity' named entity 'risk factors' named entity 'herd immunity' named entity 'herd immunity' named entity 'livestock' named entity 'seropositivity' named entity 'cattle' named entity '95% CI' named entity 'sheep' named entity 'antigen' named entity 'Gaussian process' named entity 'infection' named entity '95% CI' named entity 'variance' named entity 'sheep' named entity 'seropositivity' named entity 'vaccination' named entity 'Rwanda' named entity 'seropositive' named entity 'questionnaire' named entity 'cattle' named entity '95% CI' named entity 'cattle' named entity 'antibodies' named entity 'sheep' named entity 'maternal antibodies' named entity 'generalized additive model' named entity 'IgG antibodies' named entity 'sheep' named entity 'vaccination' named entity 'vector-borne disease' named entity 'virus' named entity 'factor analysis' named entity 'Stata' named entity 'Optical density' named entity 'seropositive' named entity 'Stata' named entity 'univariate analysis' named entity 'Black dots'

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