About: Investigating the introduction of porcine epidemic diarrhea virus into an Ohio swine operation

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About: Investigating the introduction of porcine epidemic diarrhea virus into an Ohio swine operation Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Investigating the introduction of porcine epidemic diarrhea virus into an Ohio swine operation
Creator	Davis, Matt Price, Todd Bowman, Andrew Krogwold, Roger Moeller, Steven
Source	Medline; PMC
abstract	BACKGROUND: Porcine Epidemic Diarrhea virus (PEDV) is a highly transmissible coronavirus that causes a severe enteric disease that is particularly deadly for neonatal piglets. Since its introduction to the United States in 2013, PEDV has spread quickly across the country and has caused significant financial losses to pork producers. With no fully licensed vaccines currently available in the United States, prevention and control of PEDV disease is heavily reliant on biosecurity measures. Despite proven, effective biosecurity practices, multiple sites and production stages, within and across designated production flows in an Ohio swine operation broke with confirmed PEDV in January 2014, leading the producer and attending veterinarian to investigate the route of introduction. CASE PRESENTATION: On January 12, 2014, several sows within a production flow were noted with signs of enteric illness. Within a few days, illness had spread to most of the sows in the facility and was confirmed by RT-PCR to be PEDV. Within a short time period, confirmed disease was present on multiple sites within and across breeding and post weaning production flows of the operation and mortality approached 100% in neonatal piglets. After an epidemiologic investigation, an outsourced, pelleted piglet diet was identified for assessment, and a bioassay, where naïve piglets were fed the suspected feed pellets, was initiated to test the pellets for infectious PEDV. CONCLUSIONS: The epidemiological investigation provided strong evidence for contaminated feed as the source of the outbreak. In addition, feed pellets collected from unopened bags at the affected sites tested positive for PEDV using RT-PCR. However, the bioassay study was not able to show infectivity when feeding the suspected feed pellets to a small number of naïve piglets. The results highlight the critical need for surveillance of feed and feed components to further define transmission avenues in an effort to limit the spread of PEDV throughout the U.S. swine industry.
has issue date	2015-02-15(xsd:dateTime)
bibo:doi	10.1186/s12917-015-0348-2
bibo:pmid	25881144
has license	cc-by
sha1sum (hex)	7e55726d345571690d0e3046664cfac5003c2a89
schema:url	https://doi.org/10.1186/s12917-015-0348-2
resource representing a document's title	Investigating the introduction of porcine epidemic diarrhea virus into an Ohio swine operation
has PubMed Central identifier	PMC4334577
has PubMed identifier	25881144
schema:publication	BMC Vet Res
resource representing a document's body	covid:7e55726d345571690d0e3046664cfac5003c2a89#body_text
is schema:about of	named entity 'EFFECTIVE' named entity 'VACCINES' named entity 'TO INVESTIGATE' named entity 'INFECTIVITY' named entity 'PRESENT' named entity 'ILLNESS' named entity 'MEASURES' named entity 'CONFIRMED' named entity 'BIOSECURITY' named entity 'SMALL' named entity 'MOST OF' named entity 'OHIO' named entity 'CASE PRESENTATION' named entity 'TO TEST' named entity 'LICENSED' named entity 'IS A' named entity 'PORCINE EPIDEMIC DIARRHEA VIRUS' named entity 'NEED FOR' named entity 'DIET' named entity 'CONTAMINATED' named entity 'FULLY' named entity 'TESTED' named entity 'SOWS' named entity 'DESIGNATED' named entity 'BIOASSAY' named entity 'FED' named entity 'STUDY' named entity '100%' named entity 'PROVEN' named entity 'FLOW' named entity 'FEED' named entity 'INFECTIOUS' named entity 'SPREAD' named entity 'signs' named entity 'outsourced' named entity 'swine' named entity 'pelleted' named entity 'biosecurity' named entity 'investigate' named entity '2014' named entity 'flow' named entity 'pork' named entity 'disease' named entity 'mortality' named entity 'swine' named entity 'SWINE' named entity 'PELLETS' named entity 'AFFECTED' named entity 'FINANCIAL' named entity 'ATTENDING' named entity 'SEVERE' named entity 'OUTSOURCED' named entity 'SIGNS' named entity 'CONCLUSIONS' named entity 'PRODUCERS' named entity 'CURRENTLY' named entity 'SUSPECTED' named entity 'COLLECTED' named entity 'SHORT' named entity 'LIMIT' named entity 'EPIDEMIOLOGIC' named entity 'PRODUCER' named entity 'NOTED' named entity 'POSITIVE FOR' named entity 'RT-PCR' named entity 'SIGNIFICANT' named entity 'EVIDENCE FOR' named entity 'HIGHLY' named entity 'LEADING' named entity 'MORTALITY' named entity 'SURVEILLANCE' named entity 'FLOWS' named entity 'CAUSES' named entity 'INDUSTRY' named entity 'INTRODUCTION' named entity 'INVESTIGATING' named entity 'PORCINE EPIDEMIC DIARRHEA VIRUS'

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