About: Bovine adenovirus-3 as a vaccine delivery vehicle

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Bovine adenovirus-3 as a vaccine delivery vehicle
Creator	Gaba, Amit Kumar, Pankaj Makadiya, Niraj Tikoo, Suresh Ayalew, Lisanework
Source	Elsevier; Medline; PMC
abstract	Abstract The use of vaccines is an effective and relatively inexpensive means of controlling infectious diseases, which cause heavy economic losses to the livestock industry through animal loss, decreased productivity, treatment expenses and decreased carcass quality. However, some vaccines produced by conventional means are imperfect in many respects including virulence, safety and efficacy. Moreover, there are no vaccines for some animal diseases. Although genetic engineering has provided new ways of producing effective vaccines, the cost of production for veterinary use is a critical criterion for selecting the method of production and delivery of vaccines. The cost effective production and intrinsic ability to enter cells has made adenovirus vectors a highly efficient tool for delivery of vaccine antigens. Moreover, adenoviruses induce both humoral and cellular immune responses to expressed vaccine antigens. Since nonhuman adenoviruses are species specific, the development of animal specific adenoviruses as vaccine delivery vectors is being evaluated. This review summarizes the work related to the development of bovine adenovirus-3 as a vaccine delivery vehicle in animals, particularly cattle.
has issue date	2015-01-15(xsd:dateTime)
bibo:doi	10.1016/j.vaccine.2014.11.055
bibo:pmid	25498212
has license	els-covid
sha1sum (hex)	7f60c9d00f903457244719182bd27821116dcfa6
schema:url	https://doi.org/10.1016/j.vaccine.2014.11.055
resource representing a document's title	Bovine adenovirus-3 as a vaccine delivery vehicle
has PubMed Central identifier	PMC7115382
has PubMed identifier	25498212
schema:publication	Vaccine
resource representing a document's body	covid:7f60c9d00f903457244719182bd27821116dcfa6#body_text
is schema:about of	named entity 'vaccine' named entity 'development' named entity 'adenoviruses' named entity 'NEW' named entity 'HIGHLY' named entity 'CATTLE' named entity 'MEANS' named entity 'DELIVERY' named entity 'INDUCE' named entity 'VACCINE' named entity 'BEING' named entity 'SPECIFIC' named entity 'DEVELOPMENT' named entity 'VEHICLE' named entity 'EFFICIENT' named entity 'INFECTIOUS DISEASES' named entity 'CRITICAL' named entity 'TREATMENT' named entity 'VECTORS' named entity 'ANIMAL DISEASES' named entity 'PRODUCTION' named entity 'INCLUDING' named entity 'TOOL' named entity 'ANIMALS' named entity 'IS A' named entity 'ANTIGENS' named entity 'CRITERION' named entity 'ANIMAL' named entity 'VIRULENCE' named entity 'VETERINARY' named entity 'CELLULAR' named entity 'SPECIES' named entity 'EXPENSES' named entity 'EFFECTIVE' named entity 'HEAVY' named entity 'INDUSTRY' named entity 'COST' named entity 'EVALUATED' named entity 'ENTER' named entity 'METHOD' named entity 'BOVINE ADENOVIRUS' named entity 'VACCINE DELIVERY' named entity 'REVIEW' named entity 'PRODUCTIVITY' named entity 'BOVINE ADENOVIRUS' named entity 'INTRINSIC' named entity 'VEHICLE' named entity 'VACCINES' named entity 'USE OF' named entity 'NONHUMAN' named entity 'IMMUNE RESPONSES' named entity 'USE' named entity 'CONTROLLING' named entity 'GENETIC ENGINEERING' named entity 'CONVENTIONAL' named entity 'ECONOMIC' named entity 'WORK RELATED' named entity 'SELECTING' named entity 'LIVESTOCK' named entity 'RESPECTS' named entity 'CAUSE' named entity 'DECREASED' named entity 'ADENOVIRUSES' named entity 'EXPRESSED' named entity 'CELLS' named entity 'SAFETY' named entity 'LOSS' named entity 'VACCINE DELIVERY' named entity 'EFFICACY' named entity 'PRODUCING' named entity 'PROVIDED' named entity 'ADENOVIRUS' covid:arg/7f60c9d00f903457244719182bd27821116dcfa6 named entity 'specific' named entity 'infectious diseases' named entity 'cattle' named entity 'animal'

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