About: Effects of Luteolin on the Proliferation of Rat Lung Fibroblasts

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Effects of Luteolin on the Proliferation of Rat Lung Fibroblasts
Creator	Wang, Yin Gong Guo-Qing, Li, Lin-Lin Li-Na, Yang Zhang, Guo-Min
Source	Elsevier; PMC
abstract	Abstract Aim To approach the effects of luteolin on proliferation of rat lung fibroblasts. Methods The lung fibroblasts were isolated from the lungs of Sprague-Dawley rats at postnatal day 3, and were then passaged to 96-well culture plates. All cells were divide into 6 groups including normal control group, positive control group, 4×10 time, the cytomorphology of LFb, drew growth curve, determined superoxide dismutase (SOD) activity were observed. Results Luteolin at the concentration of 4×10−4, 4×10−5 mol·L−1 inhibited evidently the growth and proliferation of lung fibroblasts, and enhanced SOD activity. The density, interval and volume of lung fibroblasts became decrescent. The effects, dose-dependently, had obvious statistical significance compared with normal control group. Conclusion Luteolin can inhibit the proliferation of the lung fibroblasts in rat.
has issue date	2009-07-31(xsd:dateTime)
bibo:doi	10.1016/s1875-5364(10)60022-2
has license	els-covid
sha1sum (hex)	807ee2efd8cfa8486196e1cbb5a2b08dc8efaa6b
schema:url	https://doi.org/10.1016/s1875-5364%2810%2960022-2
resource representing a document's title	Effects of Luteolin on the Proliferation of Rat Lung Fibroblasts
has PubMed Central identifier	PMC7128257
schema:publication	Chinese Journal of Natural Medicines
resource representing a document's body	covid:807ee2efd8cfa8486196e1cbb5a2b08dc8efaa6b#body_text
is schema:about of	named entity 'lung' named entity 'lung' named entity 'CELLS' named entity 'EFFECTS' named entity 'CULTURE PLATES' named entity 'RAT LUNG' named entity 'LUNG' named entity 'APPROACH' named entity 'FIBROBLASTS' named entity 'DIVIDE' named entity 'THE LUNGS' named entity 'POSITIVE CONTROL' named entity 'INCLUDING' named entity 'PROLIFERATION' named entity '9710' named entity 'DAY 3' named entity 'AIM' named entity 'ISOLATED' named entity 'METHODS' named entity 'CONTROL GROUP' named entity 'SPRAGUE-DAWLEY RATS' named entity 'POSTNATAL DAY' named entity 'PROLIFERATION' named entity 'LUTEOLIN' named entity 'FIBROBLASTS' named entity 'LUTEOLIN' named entity 'GROUPS' named entity 'NORMAL CONTROL GROUP' named entity 'EFFECTS' named entity 'RAT LUNG' named entity 'control group' named entity 'postnatal' named entity 'lung' named entity 'rat' named entity 'morphology' named entity 'control group' named entity 'DMEM' named entity 'severe acute respiratory syndrome' named entity 'standard deviation' named entity 'brosis' named entity 'phosphatic' named entity 'statistical significance' named entity 'supernatant' named entity 'DMEM' named entity 'Fibroblasts' named entity 'trypsin' named entity 'pulmonary fibrosis' named entity 'DMEM' named entity 'Ajuga decumbens' named entity 'Luteolin' named entity 'serum' named entity 'antioxidant' named entity 'control group' named entity 'cytokines' named entity 'cell cycle stage' named entity 'control group' named entity 'therapeutic approaches' named entity 'Luteolin' named entity 'Luteolin' named entity 'fibration' named entity 'Prednisolone acetate' named entity 'Luteolin' named entity 'Luteolin' named entity 'phlegm' named entity '3, 4' named entity 'Luteolin' named entity 'amyotrophic lateral sclerosis' named entity 'phase-contrast microscopy' named entity 'DMEM' named entity 'Luteolin' named entity 'statistical significance' named entity 'pulmonary fibrosis' named entity 'Nanjing Medical University' named entity 'control group' named entity 'control group' named entity 'serum' named entity 'pulmonary fibrosis' named entity 'enzyme' named entity 'benzopyran'

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