About: COVID-19 in London, a Case Series Demonstrating Late Improvement in Survivors

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	COVID-19 in London, a Case Series Demonstrating Late Improvement in Survivors
Creator	Lockie, Christopher Vizcaychipi, Marcela Hayes, Michelle Keays, Richard Al-Hindawi, Ahmed Bmbs, Cuddihy, Joshua Davies Mbchb, Roger Mbbs, Singh Mbchb, Linsey Sisson Mbchb, Alice Sokhi, Jagdish
Source	MedRxiv
abstract	Objective To determine whether the trajectories of survivors and non-survivors are different in patients admitted to intensive care in London. Design In this case series of 15 survivors and 16 non-survivors, data from admission to discharge was collected and aligned to lowest PaO2/FiO2 ratio where aggregation and trends were demonstrated. Setting Single centre case-series in London, Intensive Care. Participants All non-survivors were included (n=16). A biased set of survivors (n=15) who were demonstrated an unexpected and rapid recovery after a prolonged period of mechanical ventilatory support. Results Respiratory failure trajectories of survivors and non-survivors were similar once aligned indicating, from a respiratory function perspective, it is difficult to identify survivors from non-survivors with some survivors improving late in their disease (day 20 - 30 from symptom onset) Non-survivors are admitted earlier in their disease (p < 0.05) and had worse organ failure requirements prior to the nadir of their respiratory funciton (p < 0.05) compard to survivors. Conclusion Analysis of multiple factors fails to differentiate between survivors and non-survivors. Even when faced with multiorgan failure, perseverance until discharge must be advocated as late improvements do occur in survivors.
has issue date	2020-05-20(xsd:dateTime)
bibo:doi	10.1101/2020.05.16.20103853
has license	medrxiv
sha1sum (hex)	8141320a3ac40ae52df834eec761a5c2b1a15d94
schema:url	https://doi.org/10.1101/2020.05.16.20103853
resource representing a document's title	COVID-19 in London, a Case Series Demonstrating Late Improvement in Survivors
resource representing a document's body	covid:8141320a3ac40ae52df834eec761a5c2b1a15d94#body_text
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