About: ACE-2 Expression in the Small Airway Epithelia of Smokers and COPD Patients: Implications for COVID-19

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About: ACE-2 Expression in the Small Airway Epithelia of Smokers and COPD Patients: Implications for COVID-19 Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	ACE-2 Expression in the Small Airway Epithelia of Smokers and COPD Patients: Implications for COVID-19
Creator	Yang, Chen Dorscheid, Delbert Hackett, Tillie-Louise Leung, Janice Shaipanich, Tawimas Sin, Don Singhera, Gurpreet Tam, Anthony
source	Medline; PMC
abstract	Smokers and individuals with COPD have increased airway expression of ACE-2, which is the entry receptor for the COVID-19 virus. This may explain the increased risk of severe COVID-19 in these subpopulations and highlight importance of smoking cessation.
has issue date	2020-04-09(xsd:dateTime)
bibo:doi	10.1183/13993003.00688-2020
bibo:pmid	32269089
has license	cc-by-nc
sha1sum (hex)	81c3ce7899d34e95e3bbbbae0fd293c88985dfa1
schema:url	https://doi.org/10.1183/13993003.00688-2020
resource representing a document's title	ACE-2 Expression in the Small Airway Epithelia of Smokers and COPD Patients: Implications for COVID-19
has PubMed Central identifier	PMC7144263
has PubMed identifier	32269089
schema:publication	Eur Respir J
resource representing a document's body	covid:81c3ce7899d34e95e3bbbbae0fd293c88985dfa1#body_text
is schema:about of	named entity 'Vancouver, British Columbia, Canada' named entity 'Airway' named entity 'VANCOUVER' named entity 'protein expression' named entity 'RNA' named entity 'COVID-19' named entity 'Smokers' named entity 'Abcam' named entity 'airway epithelia' named entity 'ACE-2' named entity 'metallocarboxypeptidase' named entity 'smoking cessation' named entity 'FEV1/FVC' named entity 'human health' named entity 'ACE-2' named entity 'ACE' named entity 'cytologic' named entity 'Protein' named entity 'control subjects' named entity 'COPD' named entity 'smokers' named entity 'BCCA' named entity 'airway epithelium' named entity 'Leica' named entity 'receptor expression' named entity 'FEV1' named entity 'infection' named entity 'COPD' named entity 'ACE-2' named entity 'homology' named entity 'bronchial epithelial cells' named entity 'COPD' named entity 'COVID-19' named entity 'COPD' named entity 'epithelial cells' named entity 'smokers' named entity 'pack-years' named entity 'genome' named entity 'ACE-2' named entity 'FEV1%' named entity 'coronavirus' named entity 'immunohistochemistry' named entity 'receptor' named entity 'COVID-19' named entity 'smokers' named entity 'up-regulate' named entity 'WHO' named entity 'SARS-CoV-2' named entity 'gene expression' named entity 'bronchoscopy' named entity 'ACE-2' named entity 'ACE-2' named entity 'COVID' named entity 'cardiovascular diseases' named entity 'virus' named entity 'Cytologic' named entity 'respiratory physician' named entity 'smokers' named entity 'ACE-2' named entity 'negative regulator' named entity 'vasoconstrictor' named entity 'antibody' named entity 'ACE-2' named entity 'smokers' named entity 'Illumina' named entity 'Multiple Comparisons' named entity 'smokers' named entity 'smokers' named entity 'gastrointestinal' named entity 'British Columbia Cancer Agency' named entity 'lung tissue' named entity 'ACE-2' named entity 'COPD' named entity 'study population'

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