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About:
Neurological Impact of Coronavirus Disease (COVID-19): Practical Considerations for the Neuroscience Community
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wasabi.inria.fr
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Type:
Academic Article
research paper
schema:ScholarlyArticle
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type
Academic Article
research paper
schema:ScholarlyArticle
isDefinedBy
Covid-on-the-Web dataset
title
Neurological Impact of Coronavirus Disease (COVID-19): Practical Considerations for the Neuroscience Community
Creator
Aysenne, Aimee
Beighley, Adam
Bui, Cuong
Carr, ;
Carr, Christopher
Dumont, Aaron
Keen, Joseph
Kilgore, Mitchell
Mathkour, Mansour
Maulucci, Christopher
Scullen, ;
Scullen, Tyler
Werner, Cassidy
Zeoli, Tyler
Zweifler, Richard
source
Elsevier; Medline; PMC; WHO
abstract
Abstract Background The coronavirus disease of 2019 (COVID-19) that is caused by infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has recently been designated a pandemic by the World Health Organization, affecting 2.7 million individuals globally as of April 25, 2020 with over 187,000 deaths. A growing body of evidence supports central nervous system (CNS) involvement. Methods We conducted a review of the literature for articles concerning COVID-19 pathophysiology, neurological manifestations, and neuroscience provider recommendations and guidelines. Results CNS manifestations range from vague non-focal complaints to severe neurologic impairment associated with encephalitis. It is unclear whether neurological dysfunction is due to direct viral injury or systemic disease. The virus may affect brainstem pathways that lead to indirect respiratory dysfunction in addition to direct pulmonary injury. Necessary adaptations in patient management, triage, and diagnosis are evolving in light of ongoing scientific and clinical findings. Conclusions This review consolidates the current body of literature regarding the neurological impact of coronaviruses, discusses the reported neurologic manifestations of COVID-19, and highlights recommendations for patient management. Specific recommendations pertaining to clinical practice for neurologists and neurosurgeons are provided.
has issue date
2020-05-06
(
xsd:dateTime
)
bibo:doi
10.1016/j.wneu.2020.04.222
bibo:pmid
32387786
has license
els-covid
sha1sum (hex)
821ac6fe434122ec2c5d6c85449b5bf32e97e44f
schema:url
https://doi.org/10.1016/j.wneu.2020.04.222
resource representing a document's title
Neurological Impact of Coronavirus Disease (COVID-19): Practical Considerations for the Neuroscience Community
has PubMed Central identifier
PMC7202815
has PubMed identifier
32387786
schema:publication
World Neurosurg
resource representing a document's body
covid:821ac6fe434122ec2c5d6c85449b5bf32e97e44f#body_text
is
schema:about
of
named entity 'disease'
named entity 'coronavirus'
named entity 'individuals'
named entity 'Coronavirus'
named entity 'COVID-19'
named entity 'DESIGNATED'
named entity 'CENTRAL NERVOUS SYSTEM'
named entity 'OF EVIDENCE'
named entity 'globally'
named entity 'evidence'
named entity 'central nervous system (CNS)'
named entity '2019'
named entity 'World Health Organization'
named entity 'SARS-CoV-2'
named entity 'COVID'
named entity 'Neurological'
named entity 'Impact of Coronavirus'
named entity 'Neuroscience'
named entity 'SARS-CoV-2'
named entity 'seizures'
named entity 'lung'
named entity 'COVID'
named entity 'health status'
named entity 'infection'
named entity 'AIS'
named entity 'Antibodies'
named entity 'ACE inhibitors'
named entity 'neurotropism'
named entity 'Telemedicine'
named entity 'neurosurgery'
named entity 'viral encephalitis'
named entity 'pediatric neurosurgery'
named entity 'neurological symptoms'
named entity 'supportive care'
named entity 'PCR'
named entity 'powered air-purifying respirator'
named entity 'PAPR'
named entity 'intubation'
named entity 'HIV'
named entity 'pleural effusion'
named entity 'respiratory illness'
named entity 'RT-PCR'
named entity 'influenza'
named entity 'pathology'
named entity 'surgical intervention'
named entity 'neurological symptoms'
named entity 'coronaviruses'
named entity 'viremia'
named entity 'COVID'
named entity 'SARS-CoV-2'
named entity 'acute respiratory distress syndrome'
named entity 'COVID'
named entity 'IgG antibody'
named entity 'cerebral hemorrhages'
named entity 'coronavirus'
named entity 'CMV'
named entity 'follow-up'
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named entity 'SARS-CoV-2'
named entity 'neuroscience'
named entity 'COVID'
named entity 'neurological disease'
named entity 'seizure'
named entity 'systematic review'
named entity 'necrotizing'
named entity 'RT-PCR'
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