About: Molecular pathology of emerging coronavirus infections

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Molecular pathology of emerging coronavirus infections Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Molecular pathology of emerging coronavirus infections
Creator	Baric, Ralph Gralinski, Lisa
topic	covid:824e4aebd39a0531625542fb7328917bb061e5a4#this
Source	Medline; PMC
abstract	Respiratory viruses can cause a wide spectrum of pulmonary diseases, ranging from mild, upper respiratory tract infections to severe and life-threatening lower respiratory tract infections, including the development of acute lung injury (ALI) and acute respiratory distress syndrome (ARDS). Viral clearance and subsequent recovery from infection require activation of an effective host immune response; however, many immune effector cells may also cause injury to host tissues. Severe acute respiratory syndrome (SARS) coronavirus and Middle East respiratory syndrome (MERS) coronavirus cause severe infection of the lower respiratory tract, with 10% and 35% overall mortality rates, respectively; however, >50% mortality rates are seen in the aged and immunosuppressed populations. While these viruses are susceptible to interferon treatment in vitro, they both encode numerous genes that allow for successful evasion of the host immune system until after high virus titres have been achieved. In this review, we discuss the importance of the innate immune response and the development of lung pathology following human coronavirus infection.
has issue date	2014-12-11(xsd:dateTime)
bibo:doi	10.1002/path.4454
bibo:pmid	25270030
has license	cc-by-nc-nd
sha1sum (hex)	824e4aebd39a0531625542fb7328917bb061e5a4
schema:url	https://doi.org/10.1002/path.4454
resource representing a document's title	Molecular pathology of emerging coronavirus infections
has PubMed Central identifier	PMC4267971
has PubMed identifier	25270030
schema:publication	J Pathol
resource representing a document's body	covid:824e4aebd39a0531625542fb7328917bb061e5a4#body_text
is http://vocab.deri.ie/void#inDataset of	proxy:http/ns.inria.fr/covid19/824e4aebd39a0531625542fb7328917bb061e5a4
is schema:about of	named entity 'SUBSEQUENT' named entity 'UPPER RESPIRATORY TRACT INFECTIONS' named entity 'VIRUS' named entity 'LIFE' named entity 'MILD' named entity 'IMMUNE SYSTEM' named entity 'CAUSE INJURY' named entity 'ACTIVATION' named entity 'WIDE' named entity 'SEVERE INFECTION' named entity 'TISSUES' named entity 'ALLOW' named entity 'GENES' named entity 'FOLLOWING' named entity 'PULMONARY DISEASES' named entity 'RECOVERY' named entity 'AGED' named entity 'THESE' named entity 'VIRUSES' named entity 'SPECTRUM' named entity 'POPULATIONS' named entity 'LUNG' named entity 'CAUSE' named entity 'HOST IMMUNE RESPONSE' named entity 'infection' named entity 'susceptible' named entity 'injury' named entity 'wide' named entity 'mild' named entity 'mortality rates' named entity 'Severe acute respiratory syndrome (SARS)' named entity 'pulmonary diseases' named entity 'ENCODE' named entity 'INCLUDING' named entity 'LOWER RESPIRATORY TRACT' named entity 'ACUTE LUNG INJURY' named entity 'MIDDLE EAST RESPIRATORY SYNDROME ' named entity 'CELLS' named entity 'NUMEROUS' named entity 'SEVERE ACUTE RESPIRATORY SYNDROME' named entity 'SUSCEPTIBLE' named entity 'IN VITRO' named entity 'LOWER RESPIRATORY TRACT INFECTIONS' named entity 'MOLECULAR PATHOLOGY' named entity 'CORONAVIRUS INFECTION' named entity 'ACUTE RESPIRATORY DISTRESS SYNDROME' named entity 'EFFECTIVE' named entity 'HAVE' named entity 'DEVELOPMENT' named entity 'REVIEW' named entity 'INFECTION' named entity 'HUMAN CORONAVIRUS' named entity 'EFFECTOR' named entity 'CORONAVIRUS' named entity 'PATHOLOGY' named entity 'VIRAL CLEARANCE' named entity 'DISCUSS' named entity 'IMMUNOSUPPRESSED' named entity 'HOST' named entity 'CORONAVIRUS INFECTIONS' named entity 'RESPIRATORY VIRUSES' named entity 'SEEN' named entity 'OVERALL MORTALITY' named entity 'HIGH' named entity '10%' named entity 'IMMUNE' named entity 'SEVERE' named entity 'TREATMENT' named entity 'INTERFERON ' named entity 'SUCCESSFUL' named entity 'MORTALITY RATES' named entity 'INNATE IMMUNE RESPONSE' named entity 'clearance' named entity 'effective' named entity 'host' named entity 'upper respiratory tract infections' named entity 'titres' named entity 'subsequent'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software