About: Personalized Risk–Benefit Ratio Adaptation of Breast Cancer Care at the Epicenter of COVID‐19 Outbreak

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About: Personalized Risk–Benefit Ratio Adaptation of Breast Cancer Care at the Epicenter of COVID‐19 Outbreak Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Personalized Risk–Benefit Ratio Adaptation of Breast Cancer Care at the Epicenter of COVID‐19 Outbreak
Creator	Di Muzio, Nadia Gentilini, Oreste Aldrighetti, Daniela Bianchini, Giampaolo Cascinu, Stefano Di Micco, Rosa Licata, Luca Panizza, Pietro Pasetti, Marcella Petrella, Giovanna Rodighiero, Mariagrazia Rognone, Alessia Sassi, Isabella Sica, Lorenzo Viale, Giulia Zambelli, Stefania Zuber, Veronica Zucchinelli, Patrizia
topic	covid:82575a6a31f143a0b0bf95b87621ee78cae6a56b#this
Source	Medline; PMC; WHO
abstract	Northern Italy has been one of the European regions reporting the highest number of COVID‐19 cases and deaths. The pandemic spread has challenged the National Health System, requiring reallocation of most of the available health care resources to treat COVID‐19‐positive patients, generating a competition with other health care needs, including cancer. Patients with cancer are at higher risk of developing critical illness after COVID‐19 infection. Thus, mitigation strategies should be adopted to reduce the likelihood of infection in all patients with cancer. At the same time, suboptimal care and treatments may result in worse cancer‐related outcome. In this article, we attempt to estimate the individual risk–benefit balance to define personalized strategies for optimal breast cancer management, avoiding as much as possible a general untailored approach. We discuss and report the strategies our Breast Unit adopted from the beginning of the COVID‐19 outbreak to ensure the continuum of the best possible cancer care for our patients while mitigating the risk of infection, despite limited health care resources. IMPLICATIONS FOR PRACTICE: Managing patients with breast cancer during the COVID‐19 outbreak is challenging. The present work highlights the need to estimate the individual patient risk of infection, which depends on both epidemiological considerations and individual clinical characteristics. The management of patients with breast cancer should be adapted and personalized according to the balance between COVID‐19‐related risk and the expected benefit of treatments. This work also provides useful suggestions on the modality of patient triage, the conduct of clinical trials, the management of an oncologic team, and the approach to patients’ and health workers’ psychological distress.
has issue date	2020-05-26(xsd:dateTime)
bibo:doi	10.1634/theoncologist.2020-0316
bibo:pmid	32412693
has license	cc-by-nc-nd
sha1sum (hex)	82575a6a31f143a0b0bf95b87621ee78cae6a56b
schema:url	https://doi.org/10.1634/theoncologist.2020-0316
resource representing a document's title	Personalized Risk–Benefit Ratio Adaptation of Breast Cancer Care at the Epicenter of COVID‐19 Outbreak
has PubMed Central identifier	PMC7272798
has PubMed identifier	32412693
schema:publication	Oncologist
resource representing a document's body	covid:82575a6a31f143a0b0bf95b87621ee78cae6a56b#body_text
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