About: Viral pathogens associated with acute lower respiratory tract infections in children younger than 5 years of age in Bulgaria

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Viral pathogens associated with acute lower respiratory tract infections in children younger than 5 years of age in Bulgaria
Creator	Angelova, Svetla Georgieva, Irina Ivanov, Ivan Korsun, Neli Mileva, Sirma Perenovska, Penka Tcherveniakova, Tatiana Trifonova, Ivelina Tzotcheva, Iren Voleva, Silvia
Source	Medline; PMC
abstract	Acute lower respiratory infections (ALRIs) are a leading cause of morbidity and hospital admissions in children. This study aimed to determine the viral etiology of these infections in children aged < 5 years during three successive epidemic seasons in Bulgaria. Nasopharyngeal and throat specimens were collected from children with bronchiolitis and pneumonia during the 2015/2016, 2016/2017, and 2017/2018 seasons. The viral etiology was determined by individual real-time PCR assays against 11 respiratory viruses. Of the 515 children examined, 402 (78.1%) were positive for at least one virus. Co-infections with two and three viruses were found in 64 (15.9%) of the infected children. Respiratory syncytial virus (RSV) was the predominant pathogen (37.5%), followed by rhinoviruses (13.8%), metapneumovirus (9.1%), adenoviruses (7%), bocaviruses (7%), influenza A(H1N1)pdm09 (4.9%), A(H3N2) (4.3%), type B (4.1%), and parainfluenza viruses 1/2/3 (2.9%). RSV-B were more prevalent than RSV-A during the three seasons. At least one respiratory virus was identified in 82.6% and 70.1% of the children with bronchiolitis and pneumonia, respectively. Respiratory viruses, especially RSV, are principal pathogens of ALRIs in children aged < 5 years. Diagnostic testing for respiratory viruses using molecular methods may lead to the reduced use of antibiotics and may assist in measures to control infection.
has issue date	2018-12-05(xsd:dateTime)
bibo:doi	10.1007/s42770-018-0033-2
bibo:pmid	30637646
has license	no-cc
sha1sum (hex)	8262ce781e5ef09f85af22e2a072d9e5e54618b3
schema:url	https://doi.org/10.1007/s42770-018-0033-2
resource representing a document's title	Viral pathogens associated with acute lower respiratory tract infections in children younger than 5 years of age in Bulgaria
has PubMed Central identifier	PMC6863252
has PubMed identifier	30637646
schema:publication	Braz J Microbiol
resource representing a document's body	covid:8262ce781e5ef09f85af22e2a072d9e5e54618b3#body_text
is schema:about of	named entity 'INFECTED' named entity 'Bulgaria' named entity 'bronchiolitis' named entity 'lower respiratory infections' named entity 'viruses' named entity 'adenoviruses' named entity 'etiology' named entity 'influenza' named entity 'RSV' named entity 'Nasopharyngeal' named entity 'viruses' named entity 'RSV' named entity 'Respiratory syncytial virus' named entity 'lower respiratory tract infections' named entity 'tracheobronchitis' named entity 'common cold' named entity 'clinical significance' named entity 'primary care' named entity 'influenza A and B viruses' named entity 'H3N2' named entity 'pathogens' named entity 'bronchiolitis' named entity 'vaccination' named entity 'RSV' named entity 'ALRI' named entity 'viruses' named entity 'RSV' named entity 'qRT-PCR' named entity 'nucleic acid' named entity 'Goka' named entity 'RSV infection' named entity 'virus' named entity 'severe pneumonia' named entity 'influenza viruses' named entity 'real-time RT-PCR' named entity 'pneumonia' named entity 'ALRI' named entity 'Spain' named entity 'wheezing' named entity 'hMPV' named entity 'Thermo Fisher Scientific' named entity 'real-time RT-PCR' named entity 'RSV' named entity 'polyester' named entity 'pneumonia' named entity 'virus' named entity 'epidemics' named entity 'ALRI' named entity 'viruses' named entity 'infection' named entity 'RSV infection' named entity 'Viral pathogens' named entity 'RSV' named entity 'pathophysiologic' named entity 'influenza' named entity 'bronchiolitis' named entity 'systematic review' named entity 'systematic review' named entity 'RSV' named entity 'antiviral treatment' named entity 'PCR' named entity 'RSV' named entity 'real-time PCR' named entity 'viral infections' named entity 'H1N1' named entity 'pathogen' named entity 'RSV' named entity 'clinical characteristics' named entity 'AdV' named entity '21.4%' named entity 'ICUs' named entity 'pathogen'

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