About: Complete Genome Sequences of the SARS-CoV: the BJ Group (Isolates BJ01-BJ04)

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Complete Genome Sequences of the SARS-CoV: the BJ Group (Isolates BJ01-BJ04)
Creator	Liu, Hong Sun, Haiyan Wei, Wei Xu, Hong Wang, Jian Li, Xiaoyu Li, Wei Wang, Jing Liu, Yong Liu, Bin Yang, Ruifu Zhang, Feng Li, Yan Wang, Jun Zhang, Yu Deng, Yongqiang Hu, Jianfei Fan, Baochang Jiang, Tao Liu, Bohua Peng, Wenming Tan, Gang Tang, Lin Yu, Man Liu, Siqi Lin, Wei Cao, Wuchun Yu, Jun Wen, Jie Bi, Shengli Han, Yujun Ji, Jia Li, Songgang Tian, Xiangjun Xu, Jing Xu, Zuyuan Yang, Huanming Zhang, Zizhang Zhu, Jingui Wu, Qingfa Ye, Jia Hu, Yongwu Li, Guoqing Shi, Jianping Duan, Shumin Deng, Yajun Gan, Yonghua Li, Ruan Li, Wenjie Li, Yuquan Lu, Fushuang Tong, Zongzhong Yi, Yao Zhou, Yongdong An Yang, Bao Cui'e Wang, E'de Qin,
source	Elsevier; Medline; PMC
abstract	Beijing has been one of the epicenters attacked most severely by the SARS-CoV (severe acute respiratory syndrome-associated coronavirus) since the first patient was diagnosed in one of the city’s hospitals. We now report complete genome sequences of the BJ Group, including four isolates (Isolates BJ01, BJ02, BJ03, and BJ04) of the SARS-CoV. It is remarkable that all members of the BJ Group share a common haplotype, consisting of seven loci that differentiate the group from other isolates published to date. Among 42 substitutions uniquely identified from the BJ group, 32 are non-synonymous changes at the amino acid level. Rooted phylogenetic trees, proposed on the basis of haplotypes and other sequence variations of SARS-CoV isolates from Canada, USA, Singapore, and China, gave rise to different paradigms but positioned the BJ Group, together with the newly discovered GD01 (GD-Ins29) in the same clade, followed by the H-U Group (from Hong Kong to USA) and the H-T Group (from Hong Kong to Toronto), leaving the SP Group (Singapore) more distant. This result appears to suggest a possible transmission path from Guangdong to Beijing/Hong Kong, then to other countries and regions.
has issue date	2016-11-28(xsd:dateTime)
bibo:doi	10.1016/s1672-0229(03)01023-4
bibo:pmid	15629030
has license	cc-by-nc-nd
sha1sum (hex)	82e80640af0a98cc07c911c9476f693c5e9a62cf
schema:url	https://doi.org/10.1016/s1672-0229%2803%2901023-4
resource representing a document's title	Complete Genome Sequences of the SARS-CoV: the BJ Group (Isolates BJ01-BJ04)
has PubMed Central identifier	PMC5172409
has PubMed identifier	15629030
schema:publication	Genomics Proteomics Bioinformatics
resource representing a document's body	covid:82e80640af0a98cc07c911c9476f693c5e9a62cf#body_text
is schema:about of	named entity 'ONE OF' named entity 'GAVE' named entity 'ATTACKED' named entity 'SEQUENCE VARIATIONS' named entity 'DATE' named entity 'SEQUENCES' named entity 'ASSOCIATED' named entity 'RISE' named entity 'MEMBERS' named entity 'DISTANT' named entity 'SYNONYMOUS' named entity 'NEWLY DISCOVERED' named entity 'CHINA' named entity 'IDENTIFIED' named entity 'DIFFERENT' named entity 'SEVERELY' named entity 'RESPIRATORY' named entity 'BEIJING' named entity 'ACUTE' named entity 'GROUP' named entity 'HONG KONG' named entity 'ROOTED' named entity 'PROPOSED' named entity 'CHANGES' named entity 'substitutions'

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