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About:
Non-invasive CPAP in mild and moderate ARDS secondary to SARS-CoV-2
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schema:ScholarlyArticle
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wasabi.inria.fr
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Type:
Academic Article
research paper
schema:ScholarlyArticle
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type
Academic Article
research paper
schema:ScholarlyArticle
isDefinedBy
Covid-on-the-Web dataset
has title
Non-invasive CPAP in mild and moderate ARDS secondary to SARS-CoV-2
Creator
Allegorico, E
Altruda, C
Arbo, P
Bosso, G
Dello Vicario, F
Minerva, V
Numis, F
Pagano, A
Pagano, Antonio
Porta, G
Russo, T
Serra, C
T°, Russo
Vicario, Dello
Source
Elsevier; Medline; PMC
abstract
BACKGROUND: During the COVID-19 outbreak, a very high number of infected patients developed pneumonia and many of them complicated with acute respiratory distress syndrome. The optimal management of respiratory failure and the role of lung ultrasound imaging in the evaluation of efficacy of treatment are unknown. METHODS: In March 2020 we treated 18 patients with mild and moderate ARDS secondary to SARS-CoV-2 with non-invasive continuous positive airway pressure therapy (NI-CPAP). All patients underwent lung ultrasound imaging to verify the entity of lung recruitment after NI-CPAP initiation. RESULTS: After one hour of treatment we observed a significant improvement in PaO2/FiO2 ratio in 10 patients. Notably, only 50% of them reached an effective improvement in lung aeration detectable with lung ultrasound. In the other 50% or patients the improvement in PaO2/FiO2 might be related to blood redistribution and reverse of hypoxic vasoconstriction. CONCLUSION: NI- CPAP is a valid therapeutic option in mild and moderate ARDS secondary SARS-CoV-2. Lung recruitment detected by means of lung ultrasound is a relevant but not the exclusive mechanism that underlies the therapeutic efficacy of NI-CPAP in this clinical setting.
has issue date
2020-07-03
(
xsd:dateTime
)
bibo:doi
10.1016/j.resp.2020.103489
bibo:pmid
32629100
has license
no-cc
sha1sum (hex)
84347d16f283c16a82903210c8b63239c05d59b2
schema:url
https://doi.org/10.1016/j.resp.2020.103489
resource representing a document's title
Non-invasive CPAP in mild and moderate ARDS secondary to SARS-CoV-2
has PubMed Central identifier
PMC7332943
has PubMed identifier
32629100
schema:publication
Respir Physiol Neurobiol
resource representing a document's body
covid:84347d16f283c16a82903210c8b63239c05d59b2#body_text
is
schema:about
of
covid:arg/84347d16f283c16a82903210c8b63239c05d59b2
named entity 'CPAP'
named entity 'SARS-CoV-2'
named entity 'continuous positive airway pressure'
named entity 'lung'
named entity 'lung'
named entity 'Lung'
named entity 'ultrasound'
named entity 'non-invasive'
named entity 'SARS-CoV-2'
named entity 'clinical setting'
named entity 'PaO2/FiO2 ratio'
named entity 'Respiratory Physiology'
named entity 'chest wall'
named entity 'hypoxemia'
named entity 'COVID-19'
named entity 'ARDS'
named entity 'tomography'
named entity 'D-Dimer'
named entity 'FiO2'
named entity 'CPAP'
named entity 'infectious disease'
named entity 'partial pressure'
named entity 'ARDS'
named entity 'NIV'
named entity 'Thorax'
named entity 'ARDS'
named entity 'Coronavirus'
named entity 'ultrasound'
named entity 'lung tissue'
named entity 'invasive mechanical ventilation'
named entity 'two-tailed test'
named entity 'ARDS'
named entity 'CPAP'
named entity 'PaO2/FiO2'
named entity 'nursing staff'
named entity 'ventilation/perfusion ratio'
named entity 'acute respiratory failure'
named entity 'ARDS'
named entity 'lung'
named entity 'PaO2/FiO2'
named entity 'CPAP'
named entity 'NIV'
named entity 'Venturi mask'
named entity 'PaO2/FiO2 ratio'
named entity 'CPAP'
named entity 'COVID-19'
named entity 'PaO2/FiO2'
named entity 'Samsung'
named entity 'invasive ventilation'
named entity 'mortality rate'
named entity 'hypoxic vasoconstriction'
named entity 'lung'
named entity 'PaO2/FiO2 ratio'
named entity 'lateral'
named entity 'PEEP'
named entity 'ANOVA'
named entity 'pulmonary complications'
named entity 'COVID-19 infection'
named entity 'FiO2'
named entity 'alveoli'
named entity 'multiorgan failure'
named entity 'PEEP'
named entity 'non-rebreather mask'
named entity 'prognosis'
named entity 'FiO2'
named entity 'chest imaging'
named entity 'lymphocytes'
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