About: Current concepts in the prevention of pathogen transmission via blood/plasma-derived products for bleeding disorders

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Current concepts in the prevention of pathogen transmission via blood/plasma-derived products for bleeding disorders
Creator	Canaro, Mariana Navarro, David Tiede, Andreas Güertler, Lutz Federico Perno, Carlo Ironside, James Minno, Giovanni
Source	Elsevier; Medline; PMC
abstract	Abstract The pathogen safety of blood/plasma-derived products has historically been a subject of significant concern to the medical community. Measures such as donor selection and blood screening have contributed to increase the safety of these products, but pathogen transmission does still occur. Reasons for this include lack of sensitivity/specificity of current screening methods, lack of reliable screening tests for some pathogens (e.g. prions) and the fact that many potentially harmful infectious agents are not routinely screened for. Methods for the purification/inactivation of blood/plasma-derived products have been developed in order to further reduce the residual risk, but low concentrations of pathogens do not necessarily imply a low level of risk for the patient and so the overall challenge of minimising risk remains. This review aims to discuss the variable level of pathogenic risk and describes the current screening methods used to prevent/detect the presence of pathogens in blood/plasma-derived products.
has issue date	2016-01-31(xsd:dateTime)
bibo:doi	10.1016/j.blre.2015.07.004
bibo:pmid	26381318
has license	els-covid
sha1sum (hex)	84c977e07f895215385e49ed5791d1d39eb71589
schema:url	https://doi.org/10.1016/j.blre.2015.07.004
resource representing a document's title	Current concepts in the prevention of pathogen transmission via blood/plasma-derived products for bleeding disorders
has PubMed Central identifier	PMC7115716
has PubMed identifier	26381318
schema:publication	Blood Reviews
resource representing a document's body	covid:84c977e07f895215385e49ed5791d1d39eb71589#body_text
is schema:about of	named entity 'pathogens' named entity 'risk' named entity 'sensitivity' named entity 'products' named entity 'licenses' named entity 'RESIDUAL RISK' named entity 'CURRENT' named entity 'BUT' named entity 'HAVE' named entity 'CONCERN' named entity 'PURIFICATION' named entity 'MEASURES' named entity 'INCLUDE' named entity 'PATHOGEN' named entity 'SCREENING' named entity 'USED' named entity 'RISK' named entity 'TO PREVENT' named entity 'RELIABLE' named entity 'ORDER' covid:arg/84c977e07f895215385e49ed5791d1d39eb71589 named entity 'NC-' named entity 'AIMS' named entity 'THESE' named entity 'PLASMA' named entity 'PATHOGENS' named entity 'METHODS' named entity 'LEVEL' named entity 'IN BLOOD' named entity 'TO INCREASE' named entity 'TO DISCUSS' named entity 'CURRENT' named entity 'PRESENCE OF' named entity 'SUBJECT' named entity 'REASONS' named entity 'PATIENT' named entity 'LOW LEVEL' named entity 'PREVENTION OF' named entity 'DOES' named entity 'CONCENTRATIONS' named entity 'DERIVED' named entity 'PRODUCTS' named entity 'BLEEDING DISORDERS' named entity 'CONCEPTS' named entity 'DERIVED' named entity 'PATHOGEN TRANSMISSION' named entity 'LICENSE' named entity 'PRODUCTS' named entity 'BLOOD' named entity 'COMMUNITY' named entity 'OVERALL' named entity 'FACT' named entity 'OCCUR' named entity 'REDUCE' named entity 'LACK' named entity 'DO NOT' named entity 'ORG' named entity 'VARIABLE' named entity 'SIGNIFICANT' named entity 'PRIONS' named entity 'BLOOD' named entity 'MEDICAL' named entity 'OF RISK' named entity 'BLOOD SCREENING' named entity 'DONOR SELECTION' named entity 'PATHOGENIC' named entity 'SENSITIVITY' named entity 'LOW' named entity 'INFECTIOUS AGENTS' named entity 'SCREENING TESTS' named entity 'SAFETY' named entity 'REVIEW' named entity 'HARMFUL' named entity 'CHALLENGE' named entity 'PATHOGEN TRANSMISSION'

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