About: Neck circumference as reliable predictor of mechanical ventilation support in adult inpatients with COVID‐19: A multicentric prospective evaluation

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About: Neck circumference as reliable predictor of mechanical ventilation support in adult inpatients with COVID‐19: A multicentric prospective evaluation Goto Sponge NotDistinct Permalink

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Neck circumference as reliable predictor of mechanical ventilation support in adult inpatients with COVID‐19: A multicentric prospective evaluation
Creator	Berlot, Giorgio Borgo, Del Campagna, Giuseppe Cesareo, Roberto Cosmo, \| Dal, Eugenia De Cristofaro, Paolo Di Bella, Stefano Giacomazzi, Donatella Leonetti, Frida Luzzati, Roberto Macchini, Elisabetta Manfrini, Silvia Masala, Renato Ottaviani, \| Palermo, Andrea Quintavalle, Francesco Ridola, Lorenzo Roman-Pognuz, Erik Sambataro, Gianluca Sanson, Gianfranco Zerbato, Verena
Source	Medline; PMC
abstract	AIMS: COVID‐19 is especially severe for elderly subjects with cardiometabolic and respiratory comorbidities. Neck circumference (NC) has been shown to be strongly related to cardiometabolic and respiratory illnesses even after adjustment for body mass index (BMI). We performed a prospective study to investigate the potential of NC to predict the need for invasive mechanical ventilation (IMV) in adult COVID‐19 inpatients. MATERIALS AND METHODS: We prospectively and consecutively enrolled COVID‐19 adult patients admitted to dedicated medical wards of two Italian hospitals from 25 March to 7 April 2020. On admission, clinical, biochemical and anthropometric data, including BMI and NC were collected. As primary outcome measure, the maximum respiratory support received was evaluated. Follow‐up time was 30 days from hospital admission. RESULTS: We enrolled 132 subjects (55.0‐75.8 years, 32% female). During the study period, 26 (19.7%) patients underwent IMV. In multivariable logistic regression analyses, after adjusting for age, sex, diabetes, hypertension and COPD, NC resulted independently and significantly associated with IMV risk (adjusted OR 1.260—per 1 cm increase 95% CI:1.120‐1.417; P < .001), with a stronger association in the subgroup with BMI ≤30 Kg/m(2) (adjusted OR 1.526; 95% CI:1.243‐1.874; P < .001). NC showed a good discrimination power in predicting patients requiring IMV (AUC 0.783; 95% CI:0.684‐0.882; P < .001). In particular, NC > 40.5 cm (>37.5 for females and >42.5 for males) showed a higher and earlier IMV risk compared to subjects with lower NC (Log‐rank test: P < .001). CONCLUSIONS: NC is an easy to measure parameter able to predict the need for IMV in adult COVID‐19 inpatients.
has issue date	2020-06-14(xsd:dateTime)
bibo:doi	10.1002/dmrr.3354
bibo:pmid	32484298
has license	no-cc
sha1sum (hex)	870cfa0f8660253d83460a6fc6962b4ab8d7b45b
schema:url	https://doi.org/10.1002/dmrr.3354
resource representing a document's title	Neck circumference as reliable predictor of mechanical ventilation support in adult inpatients with COVID‐19: A multicentric prospective evaluation
has PubMed Central identifier	PMC7300447
has PubMed identifier	32484298
schema:publication	Diabetes Metab Res Rev
resource representing a document's body	covid:870cfa0f8660253d83460a6fc6962b4ab8d7b45b#body_text
is schema:about of	named entity 'Neck' named entity 'respiratory' named entity 'investigate' named entity 'COVID-19' named entity 'circumference' named entity 'respiratory illnesses' named entity 'prospective study' named entity 'reliable' named entity 'invasive mechanical ventilation' named entity 'cardiometabolic' named entity 'body mass index' named entity 'respiratory illnesses' named entity 'BMI' named entity 'mechanical ventilation' named entity 'IMV' named entity 'obesity' named entity 'BMI' named entity 'comorbidity' named entity 'atherosclerosis' named entity 'tocilizumab' named entity 'BMI' named entity 'comorbidities' named entity 'prospective study' named entity 'Body weight' named entity 'albumin' named entity 'higher risk' named entity 'angiotensin converting enzyme inhibitors' named entity 'anthropometric' named entity '95% CI' named entity 'BMI' named entity 'IMV' named entity 'body mass index' named entity 'study population' named entity 'treat patients' named entity 'platelet count' named entity 'diabetes' named entity 'liver diseases' named entity 'short-term' named entity 'IMV' named entity 'respiratory support' named entity 'respiratory support' named entity 'azithromycin' named entity 'BMI' named entity 'IMV' named entity 'angiotensin II receptor blockers' named entity 'chronic lung disease' named entity 'ICU' named entity 'hospital admission' named entity 'hospital admission' named entity 'SARS-CoV-2 pandemic' named entity 'ROC analysis' named entity 'insulin resistance' named entity 'data analysis' named entity 'oxygen therapy' named entity 'study population' named entity 'Declaration of Helsinki' named entity 'C-reactive protein' named entity 'pneumonia' named entity 'discrimination' named entity 'remdesivir'

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