About: Clinical course of COVID-19 in patients with pre-existing decompensated cirrhosis: initial report from China

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About: Clinical course of COVID-19 in patients with pre-existing decompensated cirrhosis: initial report from China Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Clinical course of COVID-19 in patients with pre-existing decompensated cirrhosis: initial report from China
Creator	Li, Xiaodan Li, Xinyu Liu, Tao Yang, Hua Liu, Yanna Qi, Xiaolong Wang, Jitao Jiang, Zicheng Kawada, Norifumi Shi, Jindong Shiv, · Takehara, Tetsuo Wang, Fengmei Wang, Zhengyan Xiang, Huihua Don, · Maruyama, Hitoshi Rockey, C Sarin, Kumar
Source	Medline; PMC
abstract	BACKGROUND: The clinical characteristics and disease course in COVID-19 patients with pre-existing decompensated cirrhosis has not been described so far. METHODS: In this case series, we report three patients with confirmed COVID-19 and pre-existing decompensated cirrhosis from three hospitals in Hubei, the epicenter of the outbreak in China. RESULT: Patient 1 was a 53-year-old man with hepatitis B virus-related cirrhosis, portal hypertension, and ascites. Though receiving intensive support, he died of irreversible multiple organ dysfunction syndrome 48 days after the onset of the illness. Patient 2 was a 75-year-old woman with a history of schistosomiasis-related cirrhosis, portal hypertension, and ascites. Her family members requested that invasive rescue measures not be undertaken, and she died of acute respiratory distress syndrome 40 days after presenting with COVID-19 infection. Patient 3 was an 87-year-old man with alcohol-related cirrhosis, portal hypertension, and esophageal variceal hemorrhage. He was discharged from the hospital 29 days after illness onset. CONCLUSION: The case series raise the possibility that decompensated cirrhosis may be a risk factor for a poor outcome in patients with COVID-19.
has issue date	2020-05-22(xsd:dateTime)
bibo:doi	10.1007/s12072-020-10051-z
bibo:pmid	32440857
has license	no-cc
sha1sum (hex)	87fd38e0c105b0c9f2a99fd6e9517f89279bd3a4
schema:url	https://doi.org/10.1007/s12072-020-10051-z
resource representing a document's title	Clinical course of COVID-19 in patients with pre-existing decompensated cirrhosis: initial report from China
has PubMed Central identifier	PMC7242176
has PubMed identifier	32440857
schema:publication	Hepatol Int
resource representing a document's body	covid:87fd38e0c105b0c9f2a99fd6e9517f89279bd3a4#body_text
is schema:about of	named entity '40 days' named entity 'measures' named entity 'The' named entity 'patients' named entity 'requested' named entity 'hospitals' named entity 'hospital' named entity 'SCHISTOSOMIASIS' named entity 'HISTORY OF' named entity 'HER FAMILY' named entity 'possibility' named entity 'decompensated' named entity 'variceal' named entity 'hemorrhage' named entity 'died' named entity 'receiving' named entity 'Patient' named entity 'ascites' named entity 'hepatitis B' named entity 'support' named entity 'portal hypertension' named entity 'COVID-19' named entity 'rescue' named entity 'cirrhosis' named entity 'esophageal variceal' named entity 'acute respiratory distress syndrome' named entity 'COVID' named entity 'case series' named entity 'Hubei' named entity 'hemorrhage' named entity 'COVID' named entity 'outbreak in China' named entity 'liver' named entity 'COVID' named entity 'decompensated cirrhosis' named entity 'aspartate transaminase' named entity 'alkaline phosphatase' named entity 'COVID' named entity 'COVID' named entity 'sputum' named entity 'dizziness' named entity 'cirrhosis' named entity 'cryoprecipitate' named entity 'glutathione' named entity 'COVID' named entity 'China' named entity 'COVID' named entity 'COVID' named entity 'reverse-transcriptase' named entity 'SARS-CoV-2' named entity 'decompensated cirrhosis' named entity 'Wuhan' named entity 'End-stage Liver Disease' named entity 'IgG' named entity 'Chest CT' named entity 'MELD' named entity 'decompensated cirrhosis' named entity 'medical care' named entity 'fever' named entity 'chronic kidney disease' named entity 'hepatic encephalopathy' named entity 'Hubei' named entity 'ICU'

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