About: Seroepidemiological Study on SARS-CoV IgG Antibodies of Different Populations from Several Areas

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Seroepidemiological Study on SARS-CoV IgG Antibodies of Different Populations from Several Areas
Creator	Chen, Qing Cao, Cheng Chu, Xin-Wei Li, Lin-Hai Ma, Qing-Jun Shi, Yu-Ling Wang, Yun-Long Yu, Shou-Yi
Source	Medline; PMC
abstract	OBJECTIVE: In order to investigate the clinical and epidemiological rules of severe acute respiratory syndrome (SARS), rates and levels SARS coronavirus (SARS-CoV) IgG antibodies of the patients and community populations from several areas were detected. METHODS: Indirect immunofluorescent assay (IFA) and double-antigen sandwich enzyme-linked immunosorbent assay (ELISA) were used to detect the SARS coronavirus-specific IgG antibodies in sera of 1700, including 1453 general populations from Hongkong, Marco, Guangzhou and Peking and 257 SARS patients from Guangzhou and Peking. The dynamics of the serum antibodies of SARS patients were observed from 3 to 360 days after onset of symptoms. RESULTS: 90% of 257 patient serum specimens after 20 days of disease onset showed positive SARS-CoV IgG either using ELISA or IFA. 257 SARS patients, antibodies titers increased steadily in early 4 to 6 months after onset of SARS. The titers of most cases came to the peak in the 6th month. then antibodies titers declined rapidly in some cases. However, all specimens still were positive for SARS-CoV IgG in the 48th month. CONCLUSIONS: This study suggest that few inapparent infectious patients exist during SARS epidemic. Serum IgG antibodies has diagnostic value for SARS in the late course of disease and the antibodies present more than 48 months.
has issue date	2005-06-01(xsd:dateTime)
bibo:pmid	23674957
has license	cc-by
sha1sum (hex)	896cfa254a80c192a7aa872d955e750d6280e071
resource representing a document's title	Seroepidemiological Study on SARS-CoV IgG Antibodies of Different Populations from Several Areas
has PubMed Central identifier	PMC3614584
has PubMed identifier	23674957
schema:publication	Int J Biomed Sci
resource representing a document's body	covid:896cfa254a80c192a7aa872d955e750d6280e071#body_text
is schema:about of	named entity 'investigate' named entity 'DECLINED' named entity 'AREAS' named entity 'RULES' named entity 'VALUE' named entity 'EPIDEMIC' named entity 'STUDY' named entity 'PEKING' named entity 'RESULTS' named entity 'USING' named entity 'GENERAL' named entity 'MARCO' named entity 'CONCLUSIONS' named entity 'RATES' named entity 'DOUBLE' named entity '48 MONTHS' named entity 'SERA' named entity 'LEVELS' named entity 'LATE' named entity 'DIAGNOSTIC' named entity 'POPULATIONS' named entity 'PATIENT' named entity 'DETECTED' named entity 'DYNAMICS' named entity '360' named entity 'INCREASED' named entity 'INCLUDING' named entity 'PRESENT' named entity 'DAYS' named entity 'SANDWICH' named entity 'METHODS' named entity 'INFECTIOUS' named entity 'DISEASE' named entity 'SCI' named entity 'COMMUNITY' named entity 'POSITIVE' named entity 'CAME' named entity '6TH' named entity 'IFA' named entity 'IMMUNOFLUORESCENT' named entity 'EITHER' named entity 'ORDER' named entity 'SERUM' named entity 'ENZYME-LINKED IMMUNOSORBENT ASSAY' named entity 'DIFFERENT' named entity 'SEROEPIDEMIOLOGICAL STUDY' named entity 'AREAS' named entity 'BIOMED' named entity 'SEVERE ACUTE RESPIRATORY SYNDROME' named entity 'SARS' named entity 'THE PEAK' named entity 'PATIENTS' named entity 'DISEASE ONSET' named entity 'TO DETECT' named entity 'OBSERVED' named entity 'IGG' named entity 'HONGKONG' named entity 'SARS-COV' named entity 'IGG' named entity 'ONSET OF SYMPTOMS' named entity 'TO INVESTIGATE' named entity 'CLINICAL' named entity 'MONTH' named entity 'COURSE' named entity '90%' named entity 'SPECIMENS' named entity 'ONSET OF' named entity 'USED' named entity 'EARLY' named entity 'ELISA' named entity 'INDIRECT' named entity 'POPULATIONS' named entity 'EXIST' named entity 'SPECIFIC' named entity 'SARS CORONAVIRUS' named entity 'ANTIGEN'

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