About: Multi-scale problem in the model of RNA virus evolution

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About: Multi-scale problem in the model of RNA virus evolution Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Multi-scale problem in the model of RNA virus evolution
Creator	Korobeinikov, Andrei Archibasov, Aleksei Sobolev, Vladimir
Source	PMC
abstract	A mathematical or computational model in evolutionary biology should necessary combine several comparatively fast processes, which actually drive natural selection and evolution, with a very slow process of evolution. As a result, several very different time scales are simultaneously present in the model; this makes its analytical study an extremely difficult task. However, the significant difference of the time scales implies the existence of a possibility of the model order reduction through a process of time separation. In this paper we conduct the procedure of model order reduction for a reasonably simple model of RNA virus evolution reducing the original system of three integro-partial derivative equations to a single equation. Computations confirm that there is a good fit between the results for the original and reduced models.
has issue date	2016-06-01(xsd:dateTime)
bibo:doi	10.1088/1742-6596/727/1/012007
bibo:pmid	32288778
has license	cc-by
sha1sum (hex)	89f8f963c728e580663a6eccdabaf49dcaa977ff
schema:url	https://doi.org/10.1088/1742-6596/727/1/012007
resource representing a document's title	Multi-scale problem in the model of RNA virus evolution
has PubMed Central identifier	PMC7106948
has PubMed identifier	32288778
schema:publication	J Phys Conf Ser
resource representing a document's body	covid:89f8f963c728e580663a6eccdabaf49dcaa977ff#body_text
is schema:about of	named entity 'time' named entity 'reducing' named entity 'implies' named entity 'RNA virus' named entity 'SYSTEM' named entity 'VERY SLOW' named entity 'FAST' named entity 'SIGNIFICANT' named entity 'RNA VIRUS' named entity 'ORDER' named entity 'ITS' covid:arg/89f8f963c728e580663a6eccdabaf49dcaa977ff named entity 'mathematical' named entity 'scales' named entity 'scales' named entity 'evolution' named entity 'process' named entity 'model order reduction' named entity 'equations' named entity 'simple' named entity 'time scales' named entity 'evolutionary biology' named entity 'model order reduction' named entity 'mathematical or computational model' named entity 'evolution' named entity 'partial derivative' named entity 'Multi-scale' named entity '3, 4' named entity 'HIV' named entity 'virus' named entity 'virus' named entity 'evolution' named entity 'thymus' named entity 'orders of magnitude' named entity 'fitness landscape' named entity 'evolution' named entity 'thymus' named entity 'time scales' named entity 'virus' named entity 'phenotype' named entity 'virus' named entity 'mutation' named entity 'numerical analysis' named entity 'immune response' named entity 'phenotype' named entity 'life cycle' named entity 'drug resistance' named entity 'infection' named entity 'RNA virus' named entity 'evolution' named entity 'HIV' named entity 'immune response' named entity 'phenotype' named entity 'evolutionary biology' named entity 'time scales' named entity 'HIV' named entity 'evolvability' named entity 'evolution' named entity 'virus' named entity 'experimental studies' named entity 'phenotypes' named entity 'evolution' named entity 'phenotype' named entity 'virus' named entity 'virus' named entity 'evolutionary biology' named entity 'genotypes' named entity 'evolution' named entity 'virus' named entity 'mortality rates' named entity 'generation time' named entity 'RNA virus' named entity 'basic reproduction number' named entity 'mechanistic model' named entity 'orders of magnitude' named entity 'mathematical model' named entity 'evolutionary biology' named entity 'virions' named entity 'basic reproduction number'

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