About: Powered Air Purifying Respirator (PAPR) restores the N95 face mask induced cerebral hemodynamic alterations among Healthcare Workers during COVID-19 Outbreak

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About: Powered Air Purifying Respirator (PAPR) restores the N95 face mask induced cerebral hemodynamic alterations among Healthcare Workers during COVID-19 Outbreak Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Powered Air Purifying Respirator (PAPR) restores the N95 face mask induced cerebral hemodynamic alterations among Healthcare Workers during COVID-19 Outbreak
Creator	Sharma, Vijay Bharatendu, Chandra Chin, Benjamin Goh, Yihui Khoo, Deborah Leow, Aloysius Ong, Jonathan Tan, Benjamin Tsivgoulis, Georgios Chin, Amanda Teoh, Alexandrov, Andrei Chan, Amanda Foong, Wai Hock, Luen Hong, Chiew Lee, Pyng Lin Tan, Yi Ng, Elizabeth Sooi, Kenneth Tang, Jonathan Ting Ong, Shi
source	Elsevier; Medline; PMC
abstract	BACKGROUND AND AIM: COVID-19 pandemic has resulted in an unprecedented increased usage of Personal protective equipment (PPE) by healthcare-workers. PPE usage causes headache in majority of users. We evaluated changes in cerebral hemodynamics among healthcare-workers using PPE. METHODS: Frontline healthcare-workers donning PPE at our tertiary center were included. Demographics, co-morbidities and blood-pressure were recorded. Transcranial Doppler (TCD) monitoring of middle cerebral artery was performed with 2-MHz probe. Mean flow velocity (MFV) and pulsatility index (PI) were recorded at baseline, after donning N95 respirator-mask, and after donning powered air-purifying respirator (PAPR), when indicated. End-tidal carbon-dioxide (ET-CO2) pressure was recorded for participants donning PAPR in addition to the N95 respirator-mask. RESULTS: A total of 154 healthcare-workers (mean age 29 ± 12 years, 67% women) were included. Migraine was the commonest co-morbidity in 38 (25%) individuals while 123 (80%) developed de-novo headache due to N95 mask. Donning of N95 respirator-mask resulted in significant increase in MFV (4.4 ± 10.4 cm/s, p < 0.001) and decrease in PI (0.13 ± 0.12; p < 0.001) while ET-CO2 increased by 3.1 ± 1.2 mmHg (p < 0.001). TCD monitoring in 24 (16%) participants donning PAPR and N95 respirator mask together showed normalization of PI, accompanied by normalization of ET-CO2 values within 5-min. Combined use of N95 respirator-mask and PAPR was more comfortable as compared to N95 respirator-mask alone. CONCLUSION: Use of N95 respirator-mask results in significant alterations in cerebral hemodynamics. However, these effects are mitigated by the use of additional PAPR. We recommend the use of PAPR together with the N95 mask for healthcare-workers doing longer duties in the hospital wards.
has issue date	2020-10-15(xsd:dateTime)
bibo:doi	10.1016/j.jns.2020.117078
bibo:pmid	32768718
has license	no-cc
sha1sum (hex)	8acdd690ea1bd61b8ae1995a71c05e697cf81d21
schema:url	https://doi.org/10.1016/j.jns.2020.117078
resource representing a document's title	Powered Air Purifying Respirator (PAPR) restores the N95 face mask induced cerebral hemodynamic alterations among Healthcare Workers during COVID-19 Outbreak
has PubMed Central identifier	PMC7398036
has PubMed identifier	32768718
schema:publication	J Neurol Sci
resource representing a document's body	covid:8acdd690ea1bd61b8ae1995a71c05e697cf81d21#body_text
is schema:about of	named entity 'face mask' named entity 'N95' named entity 'Healthcare Workers' named entity 'anxiety' named entity 'positive pressure' named entity 'PPE' named entity 'migraine' named entity 'respirator mask' named entity 'respirator' named entity 'heart rate' named entity 'statistically significant' named entity 'hemodynamic' named entity 'transcranial Doppler' named entity 'pulsatility index' named entity 'vascular resistance' named entity 'healthcare workers' named entity 'PaCO2' named entity 'healthcare professionals' named entity 'PAPR' named entity 'capnometer' named entity 'respirator mask' named entity 'PAPR' named entity 'N95' named entity 'p-value' named entity 'respirator mask' named entity 'PAPR' named entity 'PAPR' named entity 'endotracheal intubation' named entity 'statistically significant' named entity 'N95' named entity 'headache' named entity 'PPE' named entity 'PPE' named entity 'brain tissue' named entity 'cerebral autoregulation' named entity 'Severe Acute Respiratory Syndrome' named entity 'N95' named entity 'headache' named entity 'vasodilation' named entity 'PPE' named entity 'middle cerebral arteries' named entity 'ANOVA' named entity 'hemodynamics' named entity 'CO2' named entity 'N95' named entity 'PAPR' named entity 'N95' named entity 'statistically significant' named entity 'headache' named entity 'CO2' named entity 'PAPR' named entity 'CO2' named entity 'PPE' named entity 'healthcare workers' named entity 'PAPR' named entity 'respirator mask' named entity 'informed consent' named entity 'healthcare workers' named entity 'Migraine' named entity 'CO2'

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