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About:
Rapid and accurate identification of COVID-19 infection through machine learning based on clinical available blood test results
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wasabi.inria.fr
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Type:
Academic Article
research paper
schema:ScholarlyArticle
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type
Academic Article
research paper
schema:ScholarlyArticle
isDefinedBy
Covid-on-the-Web dataset
has title
Rapid and accurate identification of COVID-19 infection through machine learning based on clinical available blood test results
Creator
Li, Junfeng
Cai, Jing
Xie,
Huang, Huirong
Li, Shuyan
Li, Yonghong
Meng, Wenbo
Tong, Chongxiang
Wu, Jiangpeng
Xie, Xiaodong
Yang, Zengwei
Zhang, Liting
Zhang, Pengyi
Zhao, Meie
Zhu, Jinhong
Source
MedRxiv
abstract
Since the sudden outbreak of coronavirus disease 2019 (COVID-19), it has rapidly evolved into a momentous global health concern. Due to the lack of constructive information on the pathogenesis of COVID-19 and specific treatment, it highlights the importance of early diagnosis and timely treatment. In this study, 11 key blood indices were extracted through random forest algorithm to build the final assistant discrimination tool from 49 clinical available blood test data which were derived by commercial blood test equipments. The method presented robust outcome to accurately identify COVID-19 from a variety of suspected patients with similar CT information or similar symptoms, with accuracy of 0.9795 and 0.9697 for the cross-validation set and test set, respectively. The tool also demonstrated its outstanding performance on an external validation set that was completely independent of the modeling process, with sensitivity, specificity, and overall accuracy of 0.9512, 0.9697, and 0.9595, respectively. Besides, 24 samples from overseas infected patients with COVID-19 were used to make an in-depth clinical assessment with accuracy of 0.9167. After multiple verification, the reliability and repeatability of the tool has been fully evaluated, and it has the potential to develop into an emerging technology to identify COVID-19 and lower the burden of global public health. The proposed tool is well-suited to carry out preliminary assessment of suspected patients and help them to get timely treatment and quarantine suggestion. The assistant tool is now available online at http://lishuyan.lzu.edu.cn/COVID2019_2/.
has issue date
2020-04-06
(
xsd:dateTime
)
bibo:doi
10.1101/2020.04.02.20051136
has license
medrxiv
sha1sum (hex)
8c0b398abd2ce9151a30e14e324a2d91b6b850ce
schema:url
https://doi.org/10.1101/2020.04.02.20051136
resource representing a document's title
Rapid and accurate identification of COVID-19 infection through machine learning based on clinical available blood test results
resource representing a document's body
covid:8c0b398abd2ce9151a30e14e324a2d91b6b850ce#body_text
is
schema:about
of
named entity 'IDENTIFICATION'
named entity 'global health'
named entity 'BASED'
named entity 'RAPID'
named entity 'GLOBAL HEALTH'
named entity 'EARLY DIAGNOSIS'
named entity 'CONCERN'
named entity 'CORONAVIRUS DISEASE 2019'
named entity 'MACHINE LEARNING'
named entity 'EVOLVED'
named entity 'DUE TO'
named entity 'TIMELY'
named entity 'BLOOD TEST RESULTS'
named entity 'AVAILABLE'
named entity 'INFORMATION'
named entity 'CLINICAL'
named entity 'TREATMENT'
named entity 'PATHOGENESIS'
named entity 'OUTBREAK'
named entity 'SUDDEN'
named entity 'SPECIFIC'
named entity 'LACK'
named entity 'RAPIDLY'
named entity 'COVID-19'
named entity 'ACCURATE'
covid:arg/8c0b398abd2ce9151a30e14e324a2d91b6b850ce
named entity 'pathogenesis'
named entity 'infection'
named entity 'COVID-19'
named entity 'MCC'
named entity 'irreplaceable'
named entity 'peer-reviewed'
named entity 'preprint'
named entity 'COVID-19'
named entity 'hematological'
named entity 'medRxiv'
named entity 'COVID'
named entity 'bioinformatics'
named entity 'creatinine'
named entity 'COVID'
named entity 'magnesium'
named entity 'Gansu Province'
named entity 'Matthews correlation coefficient'
named entity 'medRxiv'
named entity 'infection'
named entity 'global public health'
named entity 'qRT-PCR'
named entity 'web server'
named entity 'coronavirus'
named entity 'preprint'
named entity 'COVID'
named entity 'severe epidemic'
named entity 'clinical characteristics'
named entity 'platelet'
named entity 'training set'
named entity 'cough'
named entity 'COVID'
named entity 'randomly selected'
named entity 'IgG'
named entity 'COVID-19'
named entity 'validation set'
named entity 'COVID-19'
named entity 'COVID'
named entity 'preprint'
named entity 'infection'
named entity 'immunoglobulin'
named entity 'infection'
named entity 'CK-MB'
named entity 'text box'
named entity 'respiratory illness'
named entity 'chemometrics'
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