About: Group Testing for Sars-Cov-2 to Enable Rapid Scale-Up of Testing and Real-Time Surveillance of Incidence

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About: Group Testing for Sars-Cov-2 to Enable Rapid Scale-Up of Testing and Real-Time Surveillance of Incidence Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Group Testing for Sars-Cov-2 to Enable Rapid Scale-Up of Testing and Real-Time Surveillance of Incidence
Creator	Busch, Michael Hanson, Carl Bebell, Lisa Christopoulos, Katerina Gandhi, Monica Hudgens, Michael Laeyendecker, Oliver Pilcher, Christopher Pilcher, Joshua We, Acknowledgements Westreich, Daniel
source	Medline; PMC
abstract	High-throughput molecular testing for SARS-CoV-2 may be enabled by group testing in which pools of specimens are screened, and individual specimens tested only after a pool tests positive. Several labs have recently published examples of pooling strategies applied to SARS-CoV-2 specimens, but overall guidance on efficient pooling strategies is lacking. Therefore we developed a model of the efficiency and accuracy of specimen pooling algorithms based on available data on SAR-CoV-2 viral dynamics. For a fixed number of tests, we estimate that programs using group testing could screen 2 to 20 times as many specimens compared to individual testing; increase the total number of true positive infections identified; and improve the positive predictive value of results. We compare outcomes that may be expected in different testing situations and provide general recommendations for group testing implementation. A free, publicly-available web calculator is provided to help inform laboratory decisions on SARS-CoV-2 pooling algorithms.
has issue date	2020-06-27(xsd:dateTime)
bibo:doi	10.1093/infdis/jiaa378
bibo:pmid	32592581
has license	no-cc
sha1sum (hex)	8c10b05b53886f2e8264d2036d0ccfbde290307c
schema:url	https://doi.org/10.1093/infdis/jiaa378
resource representing a document's title	Group Testing for Sars-Cov-2 to Enable Rapid Scale-Up of Testing and Real-Time Surveillance of Incidence
has PubMed Central identifier	PMC7337777
has PubMed identifier	32592581
schema:publication	J Infect Dis
resource representing a document's body	covid:8c10b05b53886f2e8264d2036d0ccfbde290307c#body_text
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