About: SARS-CoV-2 (COVID-19): What do we know about children? A systematic review

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About: SARS-CoV-2 (COVID-19): What do we know about children? A systematic review Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	SARS-CoV-2 (COVID-19): What do we know about children? A systematic review
Creator	Langenberg, Claudia Mehta, Nisha Falconer, Catherine Ffph, Tom Ffpm, Hon Mbe, Tam Mrcpch, Danielle Mullins, Edward Mytton Bm, Oliver Nguyen-Van-, Jonathan
source	Medline; PMC
abstract	BACKGROUND: Few paediatric cases of COVID-19 have been reported and we know little about the epidemiology in children, though more is known about other coronaviruses. We aimed to understand the infection rate, clinical presentation, clinical outcomes and transmission dynamics for SARS-CoV-2, in order to inform clinical and public health measures. METHODS: We undertook a rapid systematic review and narrative synthesis of all literature relating to SARS-CoV-2 in paediatric populations. The search terms also included SARS-CoV and MERS-CoV. We searched three databases and the COVID-19 resource centres of eleven major journals and publishers. English abstracts of Chinese language papers were included. Data were extracted and narrative syntheses conducted. RESULTS: 24 studies relating to COVID-19 were included in the review. Children appear to be less affected by COVID-19 than adults by observed rate of cases in large epidemiological studies. Limited data on attack rate indicate that children are just as susceptible to infection. Data on clinical outcomes are scarce but include several reports of asymptomatic infection and a milder course of disease in young children, though radiological abnormalities are noted. Severe cases are not reported in detail and there are little data relating to transmission. CONCLUSIONS: Children appear to have a low observed case rate of COVID-19 but may have similar rates to adults of infection with SARS-CoV-2. This discrepancy may be because children are asymptomatic or too mildly infected to draw medical attention, be tested and counted in observed cases of COVID-19.
has issue date	2020-05-11(xsd:dateTime)
bibo:doi	10.1093/cid/ciaa556
bibo:pmid	32392337
has license	cc-by-nc-nd
sha1sum (hex)	8cfd2becd3b2b3aa12e339f64386726e69d982a8
schema:url	https://doi.org/10.1093/cid/ciaa556
resource representing a document's title	SARS-CoV-2 (COVID-19): What do we know about children? A systematic review
has PubMed Central identifier	PMC7239259
has PubMed identifier	32392337
schema:publication	Clin Infect Dis
resource representing a document's body	covid:8cfd2becd3b2b3aa12e339f64386726e69d982a8#body_text
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