About: Treatment of Ebola-related critical illness

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Treatment of Ebola-related critical illness
Creator	Fowler, R Adhikari, N Kiiza, Peter Mullin, S Teo, K
Source	PMC
abstract	PURPOSE: To explore contemporary clincial case management of patients with Ebola virus disease. METHODS: A narrative review from a clinical perspective of clinical features, diagnostic tests, treatments and outcomes of patients with Ebola virus disease. RESULTS: Substantial advances have been made in the care of patients with Ebola virus disease (EVD), precipitated by the unprecedented extent of the 2014–2016 outbreak. There has been improved point-of-care diagnostics, improved characterization of the clinical course of EVD, improved patient-optimized standards of care, evaluation of effective anti-Ebola therapies, administration of effective vaccines, and development of innovative Ebola treatment units. A better understanding of the Ebola virus disease clinical syndrome has led to the appreciation of a central role for critical care clinicians—over 50% of patients have life-threatening complications, including hypotension, severe electrolyte imbalance, acute kidney injury, metabolic acidosis and respiratory failure. Accordingly, patients often require critical care interventions such as monitoring of vital signs, intravenous fluid resuscitation, intravenous vasoactive medications, frequent diagnostic laboratory testing, renal replacement therapy, oxygen and occasionally mechanical ventilation. CONCLUSION: With advanced training and adherence to infection prevention and control practices, clinical interventions, including critical care, are feasible and safe to perform in critically ill patients. With specific anti-Ebola medications, most patients can survive Ebola virus infection.
has issue date	2020-02-13(xsd:dateTime)
bibo:doi	10.1007/s00134-020-05949-z
bibo:pmid	32055888
has license	no-cc
sha1sum (hex)	8e2010de5fab4df265b77163b210c841df1b4c43
schema:url	https://doi.org/10.1007/s00134-020-05949-z
resource representing a document's title	Treatment of Ebola-related critical illness
has PubMed Central identifier	PMC7223059
has PubMed identifier	32055888
schema:publication	Intensive Care Med
resource representing a document's body	covid:8e2010de5fab4df265b77163b210c841df1b4c43#body_text
is schema:about of	named entity 'Ebola' named entity 'NARRATIVE REVIEW' named entity 'Ebola virus disease' named entity 'EBOLA VIRUS DISEASE' named entity 'CASE MANAGEMENT' named entity 'NARRATIVE REVIEW' named entity 'EBOLA' named entity 'patients' named entity 'case management' named entity 'Ebola virus disease' named entity 'PATIENTS' named entity 'Purpose' named entity 'PURPOSE' named entity 'critical illness' named entity 'CRITICAL ILLNESS' named entity 'RELATED' named entity 'REVIEW TREATMENT'
is part of of	Treatment of Ebola-related critical illness PURPOSE: To explore contemporary clincial case management of patients with Ebola virus disease. METHODS: A narrative review from a clinical perspective of clinical features, diagnostic tests, treatments and outcomes of patients with Ebola virus disease. RESULTS: Substantial advances have been made in the care of patients with Ebola virus disease (EVD), precipitated by the unprecedented extent of the 2014–2016 outbreak. There has been improved point-of-care diagnostics, improved characterization of the clinical course of EVD, improved patient-optimized standards of care, evaluation of effective anti-Ebola therapies, administration of effective vaccines, and development of innovative Ebola treatment units. A better understanding of the Ebola virus disease clinical syndrome has led to the appreciation of a central role for critical care clinicians—over 50% of patients have life-threatening complications, including hypotension, severe electrolyte imbalance, acute kidney injury, metabolic acidosis and respiratory failure. Accordingly, patients often require critical care interventions such as monitoring of vital signs, intravenous fluid resuscitation, intravenous vasoactive medications, frequent diagnostic laboratory testing, renal replacement therapy, oxygen and occasionally mechanical ventilation. CONCLUSION: With advanced training and adherence to infection prevention and control practices, clinical interventions, including critical care, are feasible and safe to perform in critically ill patients. With specific anti-Ebola medications, most patients can survive Ebola virus infection. covid:8e2010de5fab4df265b77163b210c841df1b4c43#body_text

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