About: Cancer of Reproductive System: Receptors and Targeting Strategies

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Cancer of Reproductive System: Receptors and Targeting Strategies
Creator	Dandekar, Prajakta Jain, Ratnesh Dandekar, · Devarajan, P Devarajan, Padma Gore, M Gore, Manish Indurkar, Abhishek Indurkar, · Jain, · Puranik, A Puranik, Amita Sonowal, Bismita Sonowal, ·
Source	PMC
abstract	Carcinogenesis in the different organs of the reproductive system, particularly, prostate, ovarian, and cervical tissues, involves aberrant expression of various physiological receptors belonging to different superfamilies. This chapter provides insights into the physiological receptors that are associated with the genesis, progression, metastasis, management, as well as the prognosis of the cancers of the male and female reproductive systems. It also highlights the structural and binding characteristics of the highly predominant receptors, namely, androgen, estrogen, progesterone, and gonadotropin-releasing hormone (GnRH) receptors, which are overexpressed in these cancers and discusses various strategies to target them.
has issue date	2019-07-25(xsd:dateTime)
bibo:doi	10.1007/978-3-030-29168-6_4
has license	no-cc
sha1sum (hex)	8e379df10bdc373c8494ce5656be5718127c60c9
schema:url	https://doi.org/10.1007/978-3-030-29168-6_4
resource representing a document's title	Cancer of Reproductive System: Receptors and Targeting Strategies
has PubMed Central identifier	PMC7122620
schema:publication	Targeted Intracellular Drug Delivery by Receptor Mediated Endocytosis
resource representing a document's body	covid:8e379df10bdc373c8494ce5656be5718127c60c9#body_text
is schema:about of	named entity 'Cancer' named entity 'STRATEGIES' named entity 'ESTROGEN' named entity 'PROGNOSIS' named entity 'ORGANS' named entity 'VARIOUS' named entity 'PHYSIOLOGICAL' named entity 'belonging' named entity 'male' named entity 'female' named entity 'aberrant' named entity 'metastasis' named entity 'binding' named entity 'protein' named entity 'RFC' named entity 'HTR1A' named entity 'angiogenesis' named entity 'amino-terminal' named entity 'ligand' named entity 'contraceptives' named entity 'EGF' named entity 'GnRH' named entity 'molecule' named entity 'GnRHR' named entity 'Exemestane' named entity 'norgestrel' named entity 'Peroxisome' named entity 'GnRHR' named entity 'nuclear translocation' named entity 'PRAs' named entity 'Cyclin D1' named entity 'PRA' named entity 'sex hormones' named entity 'biochemical pathways' named entity 'antineoplastic activity' named entity 'HTR1A' named entity 'agonists' named entity 'activation function' named entity 'nanoparticles' named entity 'GnRHR' named entity 'peptide-based' named entity 'risk factors' named entity 'C-17' named entity 'Vascular endothelial growth factor' named entity 'hormone' named entity 'Selenium' named entity 'p53' named entity 'solid tumors' named entity 'estrogen' named entity 'ERα' named entity 'mammary gland' named entity 'hydroxyl groups' named entity 'prostate cancer' named entity 'Castration-resistant prostate cancer' named entity 'translocation' named entity 'Endothelin-1' named entity 'ligands' named entity 'amino acid residues' named entity 'autocrine' named entity 'highly conserved' named entity 'pharmacokinetic profile' named entity 'PR-B' named entity 'etonogestrel' named entity 'combination therapy' named entity 'tumor' named entity 'raloxifene' named entity 'DBD' named entity 'cathepsin' named entity 'trimegestone' named entity 'risk factors'

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