About: Infections in Cirrhosis

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Infections in Cirrhosis
Creator	Reddy, K Address, Ekpanyapong, Sirina
topic	covid:8e786080de814c2a20c5b47a0ed62ada342449ef#this
Source	PMC
abstract	PURPOSE OF REVIEW: Patients with cirrhosis are at high risk of developing serious infections. Bacterial infections remain the most common cause of morbidity and mortality in these patients. This review is focused on the prevalence of infections in those with cirrhosis, including multidrug-resistant (MDR) pathogens, pathogenesis of infection-related acute-on-chronic liver failure (ACLF), current treatment recommendations, and prophylactic strategies in patients with cirrhosis. RECENT FINDINGS: Recent epidemiological studies have noted an emerging prevalence of MDR bacterial infections and associated with poor prognosis, and a high rate of treatment failure and mortality. Therefore, new recommendations on empirical antibiotic use based on epidemiological data have been developed in order to improve outcomes. SUMMARY: Spontaneous bacterial peritonitis (SBP) and urinary tract infection (UTI) are the most frequent infections followed by pneumonia, cellulitis, and bacteremia, while pneumonia carries the highest risk of mortality. The incidence of MDR bacterial infections has been increasing, especially in healthcare-associated settings. Second infections that develop during hospitalization, multiple organ failures, and high MELD score are associated with poor survival. Preventive measures, early diagnosis, and adequate treatment of infections are essential key concepts in minimizing morbidity and mortality in patients with cirrhosis.
has issue date	2019-04-12(xsd:dateTime)
bibo:doi	10.1007/s11938-019-00229-2
bibo:pmid	30980335
has license	no-cc
sha1sum (hex)	8e786080de814c2a20c5b47a0ed62ada342449ef
schema:url	https://doi.org/10.1007/s11938-019-00229-2
resource representing a document's title	Infections in Cirrhosis
has PubMed Central identifier	PMC7101776
has PubMed identifier	30980335
schema:publication	Curr Treat Options Gastroenterol
resource representing a document's body	covid:8e786080de814c2a20c5b47a0ed62ada342449ef#body_text
is http://vocab.deri.ie/void#inDataset of	https://covidontheweb.inria.fr:4443/about/id/http/ns.inria.fr/covid19/8e786080de814c2a20c5b47a0ed62ada342449ef
is schema:about of	named entity 'cellulitis' named entity 'current' named entity 'focused' named entity 'Purpose' named entity 'Bacterial infections' named entity 'Cirrhosis' named entity 'MULTIPLE ORGAN FAILURES' named entity 'PURPOSE' covid:arg/8e786080de814c2a20c5b47a0ed62ada342449ef named entity 'infections' named entity 'multidrug-resistant' named entity 'infections' named entity 'MDR' named entity 'cirrhosis' named entity 'hospitalization' named entity 'Preventive' named entity 'SBP' named entity 'diagnosis' named entity 'Spontaneous bacterial peritonitis' named entity 'frequent' named entity 'mortality' named entity 'This' named entity 'antibiotic' named entity 'Infections' named entity 'antibiotic' named entity 'multidrug-resistant' named entity 'cirrhosis' named entity 'urinary tract infection' named entity 'healthcare-associated' named entity 'prognosis' named entity 'early diagnosis' named entity 'infection' named entity 'Cirrhosis' named entity 'settings' named entity 'nosocomial' named entity 'Intravenous' named entity 'SBP' named entity 'portosystemic shunting' named entity 'gold standard' named entity 'mumps' named entity 'cirrhosis' named entity 'peritonitis' named entity 'antimicrobial' named entity 'seroconversion' named entity 'varicella' named entity 'intubations' named entity 'seroconversion' named entity 'norfloxacin' named entity 'pathogen' named entity 'Vibrio' named entity 'secretion' named entity 'prophylaxis' named entity 'morbidity' named entity 'antibiotics' named entity 'SBP' named entity 'protein' named entity 'fungal infections' named entity 'ciprofloxacin' named entity 'cirrhosis' named entity 'ascites' named entity 'spontaneous bacterial peritonitis' named entity 'Proteobacteria' named entity 'cirrhosis' named entity 'SBP' named entity 'diabetes' named entity 'chronic liver disease' named entity 'gram-positive' named entity 'cirrhosis' named entity 'leukocyte' named entity 'hepatitis' named entity 'damage-associated molecular patterns' named entity 'microscopy' named entity 'pertussis' named entity 'human papilloma virus' named entity 'spp' named entity 'liver inflammation' named entity 'streptococci'

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