About: Maternal and neonatal outcomes of pregnant women with COVID-19 pneumonia: a case-control study

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Maternal and neonatal outcomes of pregnant women with COVID-19 pneumonia: a case-control study
Creator	Yang, Lin Liu, Kui Li, Na Peng, Min Chen, Lin Han, Lefei Li, Qiannan Lv, Yuxia Ouyang, Yin Sun, Guoqiang Yue, Linli
source	MedRxiv
abstract	Background The ongoing epidemics of coronavirus disease 2019 (COVID-19) have caused serious concerns about its potential adverse effects on pregnancy. There are limited data on maternal and neonatal outcomes of pregnant women with COVID-19 pneumonia. Methods We conducted a case-control study to compare clinical characteristics, maternal and neonatal outcomes of pregnant women with and without COVID-19 pneumonia. Results During January 24 to February 29, 2020, there were sixteen pregnant women with confirmed COVID-19 pneumonia and eighteen suspected cases who were admitted to labor in the third trimester. Two had vaginal delivery and the rest took cesarean section. Few patients presented respiratory symptoms (fever and cough) on admission, but most had typical chest CT images of COVID-19 pneumonia. Compared to the controls, COVID-19 pneumonia patients had lower counts of white blood cells (WBC), neutrophils, C-reactive protein (CRP), and alanine aminotransferase (ALT) on admission. Increased levels of WBC, neutrophils, eosinophils, and CRP were found in postpartum blood tests of pneumonia patients. There were three (18.8%) and two (10.5%) of the mothers with confirmed or suspected COVID-19 pneumonia had preterm delivery due to maternal complications, which were significantly higher than the control group. None experienced respiratory failure during hospital stay. COVID-19 infection was not found in the newborns and none developed severe neonatal complications. Conclusion Severe maternal and neonatal complications were not observed in pregnant women with COVID-19 pneumonia who had vaginal delivery or caesarean section. Mild respiratory symptoms of pregnant women with COVID-19 pneumonia highlight the need of effective screening on admission.
has issue date	2020-03-13(xsd:dateTime)
bibo:doi	10.1101/2020.03.10.20033605
has license	medrxiv
sha1sum (hex)	8ee1c4206000ff063b7b10405ead09cbd73b0cf6
schema:url	https://doi.org/10.1101/2020.03.10.20033605
resource representing a document's title	Maternal and neonatal outcomes of pregnant women with COVID-19 pneumonia: a case-control study
resource representing a document's body	covid:8ee1c4206000ff063b7b10405ead09cbd73b0cf6#body_text
is schema:about of	named entity 'NEONATAL' named entity 'OUTCOMES' named entity 'coronavirus disease 2019' named entity 'adverse effects' named entity 'pregnancy' named entity 'pregnancy' named entity 'COVID' named entity 'pregnant women' named entity 'COVID' named entity 'neonatal' named entity 'medRxiv' named entity 'vaginal delivery' named entity 'CT imaging' named entity 'pneumonia' named entity 'respiratory symptoms' named entity 'APGAR score' named entity 'clinical diagnosis' named entity 'COVID' named entity 'preprint' named entity 'tertiary hospital' named entity 'COVID' named entity 'COVID' named entity 'COVID' named entity 'diarrhea' named entity 'peer review' named entity 'hepatitis' named entity 'preprint' named entity 'infection' named entity '1.000' named entity 'control groups' named entity 'preprint' named entity 'Hubei' named entity 'pregnant women' named entity 'caesarean section' named entity 'preterm delivery' named entity 'RT-PCR' named entity 'SARS-CoV' named entity 'MERS-CoV' named entity 'laboratory tests' named entity 'fetal distress' named entity 'aspartate aminotransferase' named entity 'fever' named entity 'ICU' named entity 'medical records' named entity 'pregnant women' named entity 'ground glass opacity' named entity 'pneumonia' named entity 'gave birth' named entity 'vertical transmission' named entity 'COVID' named entity 'medRxiv' named entity 'pregnant women' named entity 'case-control study' named entity 'medical records' named entity 'vomiting' named entity 'tertiary hospital' named entity 'preprint' named entity 'March 13, 2020' named entity 'epidemiological' named entity 'COVID' named entity 'obstetric' named entity 'pneumonia' named entity 'control group' named entity 'data analysis' named entity 'MERS-CoV' named entity 'adverse effects' named entity 'pneumonia' named entity 'pneumonia' named entity 'SARS-CoV-2' named entity 'non-pregnant' named entity 'medRxiv' named entity 'Laboratory investigations' named entity 'respiratory symptoms' named entity 'COVID' named entity 'full-term'

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