About: Detection of respiratory viruses in gargle specimens of healthy children

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Detection of respiratory viruses in gargle specimens of healthy children
Creator	Kase, Tetsuo Hiroi, Satoshi Morikawa, Saeko
Source	Elsevier; Medline; PMC
abstract	BACKGROUND: Respiratory tract viral infection is one of the most common and important diseases in children. Polymerase chain reaction (PCR) tests are often used to detect viruses in samples, it is difficult to interpret the clinical significance of PCR positivity, which may reflect a past, imminent or active asymptomatic infection due to their high sensitivity. Although single respiratory viruses have been detected in samples from children with symptoms, other respiratory viruses can also be detected simultaneously. However, the clinical importance of these findings for the symptoms is not known. OBJECTIVES: To investigate the prevalence of respiratory viruses among children without any symptoms such as acute respiratory illness and/or fever. STUDY DESIGN: From week twenty-five 2013 to week twenty-six 2014, gargle samples were collected from children once a week and these samples were subjected to real-time PCR to detect respiratory viruses. On each sampling day, we asked the parents about their children’s health condition. RESULTS: Among the 286 samples collected, 200 were from asymptomatic children. In the asymptomatic condition, human parechovirus, adenovirus, enterovirus, rhinovirus, coronavirus 229E and HKU1 were observed in 45 episodes. In samples from symptomatic children, parainfluenza viruses, respiratory syncytial virus and coronavirus OC43 were detected in addition to those mentioned above. CONCLUSIONS: Various viruses of different species were detected in the specimens from the children regardless of their health status. It might be speculated that host factors such as the function of the immune system influence the clinical outcome of the infection. However, this needs to be studied further.
has issue date	2015-01-13(xsd:dateTime)
bibo:doi	10.1016/j.jcv.2015.01.006
bibo:pmid	25728080
has license	no-cc
sha1sum (hex)	916f40590e69b6004914559b3e6a8b8a073734b3
schema:url	https://doi.org/10.1016/j.jcv.2015.01.006
resource representing a document's title	Detection of respiratory viruses in gargle specimens of healthy children
has PubMed Central identifier	PMC7106489
has PubMed identifier	25728080
schema:publication	J Clin Virol
resource representing a document's body	covid:916f40590e69b6004914559b3e6a8b8a073734b3#body_text
is schema:about of	named entity 'SINGLE' named entity 'CONCLUSIONS' named entity 'DETECTED' named entity 'CHILDREN' named entity 'EPISODES' named entity 'CLINICAL SIGNIFICANCE' named entity 'ONE OF' named entity 'COMMON' named entity 'DIFFERENT' named entity 'ANY SYMPTOMS' named entity 'REGARDLESS' named entity 'ENTEROVIRUS' named entity 'ASYMPTOMATIC' named entity 'DIFFICULT' named entity 'THESE' named entity 'PARENTS' named entity 'ONCE A WEEK' named entity 'CORONAVIRUS OC43' named entity 'SAMPLING' named entity 'INFECTION' named entity 'CONDITION' named entity 'WEEK' named entity 'SPECIES' named entity 'TO INVESTIGATE' named entity 'HAVE' named entity 'tests' named entity 'imminent' named entity 'detect' named entity 'Various' named entity 'asymptomatic condition' named entity 'fever' named entity 'day' named entity 'gargle' named entity 'RESPIRATORY VIRUSES' named entity 'ASYMPTOMATIC INFECTION' named entity 'RESPIRATORY TRACT' named entity 'OBJECTIVES' named entity 'FINDINGS' named entity '200' named entity 'REAL-TIME PCR ' named entity 'HOST' named entity 'HEALTH STATUS' named entity 'DAY' named entity 'NEEDS' named entity 'ACTIVE' named entity 'ABOUT' named entity 'SYMPTOMATIC' named entity 'IMMINENT' named entity 'SIMULTANEOUSLY' named entity 'STUDY DESIGN' named entity 'FUNCTION' named entity 'HEALTHY' named entity 'CHILDREN' named entity 'DETECTION' named entity 'GARGLE' named entity 'VARIOUS' named entity 'THEIR' named entity 'ADDITION' named entity 'RHINOVIRUS' named entity 'DISEASES' named entity 'RESPIRATORY VIRUSES' named entity 'HIGH SENSITIVITY' named entity 'VIRUSES' named entity 'CORONAVIRUS 229E' named entity 'USED' named entity 'COLLECTED' named entity 'GARGLE' named entity 'SYMPTOMS' named entity 'TWENTY-SIX' named entity 'TO DETECT' named entity 'BACKGROUND' named entity 'PAST' named entity 'SAMPLES' named entity 'SPECIMENS' named entity 'INTERPRET' named entity 'PREVALENCE' named entity 'HEALTH CONDITION' named entity 'ADENOVIRUS' named entity 'MIGHT BE'

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