About: A Case of Steroid-Responsive, COVID-19 Immune Reconstitution Inflammatory Syndrome Following the Use of Granulocyte Colony-Stimulating Factor

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About: A Case of Steroid-Responsive, COVID-19 Immune Reconstitution Inflammatory Syndrome Following the Use of Granulocyte Colony-Stimulating Factor Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	A Case of Steroid-Responsive, COVID-19 Immune Reconstitution Inflammatory Syndrome Following the Use of Granulocyte Colony-Stimulating Factor
Creator	Kenyon, Chris Laghrib, Yassine Mertens, Jonathan
Source	Medline; PMC
abstract	We present a case report of a 54-year-old male with metastasized nasopharyngeal carcinoma presenting to the hospital with dyspnea, anorexia and fever. Examination revealed chemotherapy-induced pancytopenia. The patient tested positive for SARSCoV-2, but respiratory complications were mild. The patient was treated with granulocyte-colony stimulating factor (G-CSF) leading to amelioration of the neutropenia. However, severe acute respiratory distress syndrome (ARDS) occurred, prompting the diagnosis of immune reconstitution inflammatory syndrome (IRIS). GCSF is currently investigated as additional therapy in ARDS, but this case report emphasizes that risks and benefits must be carefully assessed. To our knowledge, this is the first case report of IRIS-induced ARDS in a COVID-19 patient.
has issue date	2020-08-17(xsd:dateTime)
bibo:doi	10.1093/ofid/ofaa326
bibo:pmid	32855992
has license	cc-by-nc-nd
sha1sum (hex)	921e7953a33961a2a4db36e5c094777b5439090d
schema:url	https://doi.org/10.1093/ofid/ofaa326
resource representing a document's title	A Case of Steroid-Responsive, COVID-19 Immune Reconstitution Inflammatory Syndrome Following the Use of Granulocyte Colony-Stimulating Factor
has PubMed Central identifier	PMC7443106
has PubMed identifier	32855992
schema:publication	Open Forum Infect Dis
resource representing a document's body	covid:921e7953a33961a2a4db36e5c094777b5439090d#body_text
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