About: High Rate of Viral Identification and Coinfections in Infants with Acute Bronchiolitis

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	High Rate of Viral Identification and Coinfections in Infants with Acute Bronchiolitis
Creator	Rodrigues, J Abramovici, S Ferreira, Avs Filho, Silva Nascimento, M Souza, A
source	Medline; PMC
abstract	OBJECTIVES: To determine the viruses and risk factors associated with hospital and intensive care unit (ICU) admissions in infants with acute bronchiolitis. INTRODUCTION: Bronchiolitis is a major cause of morbidity in infants. Widespread use of molecular-based methods has yielded new insights about its etiology, but the impact of viral etiologies on early outcomes is still unclear. METHODS: Seventy-seven infants with bronchiolitis who were under two years of age and visited an emergency unit were included. Using molecular-based methods, samples were tested for 12 different respiratory viruses. Logistic regression models were used to identify clinical and virological variables associated with the main endpoints: hospital admission and ICU admission. RESULTS: We identified at least one virus in 93.5% of patients, and coinfections were found in nearly 40% of patients. RSV was the most common pathogen (63.6%), followed by rhinovirus (39%). Identification of RSV was only associated with an increased risk of hospital admission in the univariate model. Younger age and enterovirus infection were associated with an increased risk of hospital admission, while atopy of a first-degree relative showed a protective effect. Prematurity was associated with an increased risk of admission to the ICU. Coinfections were not associated with worse outcomes. CONCLUSIONS: Molecular-based methods resulted in high rates of viral identification but did not change the significant role of RSV in acute bronchiolitis. Younger age and enterovirus infection were risk factors for hospital admission, while prematurity appeared to be a significant risk factor for admission to the ICU in acute viral bronchiolitis.
has issue date	2010-11-01(xsd:dateTime)
bibo:doi	10.1590/s1807-59322010001100014
bibo:pmid	21243286
has license	cc-by-nc
sha1sum (hex)	924dc69ab73fbedf0c55ba2f7cd22e76710512ea
schema:url	https://doi.org/10.1590/s1807-59322010001100014
resource representing a document's title	High Rate of Viral Identification and Coinfections in Infants with Acute Bronchiolitis
has PubMed Central identifier	PMC2999709
has PubMed identifier	21243286
schema:publication	Clinics (Sao Paulo)
resource representing a document's body	covid:924dc69ab73fbedf0c55ba2f7cd22e76710512ea#body_text
is schema:about of	named entity 'ASSOCIATED WITH' named entity 'INFANTS' named entity 'HOSPITAL' named entity 'acute' named entity 'VIRUSES' named entity 'INTENSIVE CARE UNIT' named entity 'ACUTE BRONCHIOLITIS' named entity 'HIGH RATE' named entity 'OBJECTIVES' named entity 'ACUTE BRONCHIOLITIS' named entity 'VIRAL IDENTIFICATION' named entity 'INFANTS' named entity 'DETERMINE' named entity 'ADMISSIONS' named entity 'RISK FACTORS' covid:arg/924dc69ab73fbedf0c55ba2f7cd22e76710512ea named entity 'determine' named entity 'rhinovirus' named entity 'median age' named entity 'enterovirus' named entity 'prospective cohort' named entity 'virus' named entity 'ICU' named entity 'Bronchiolitis' named entity 'Coinfections' named entity 'apnea' named entity 'prematurity' named entity 'Hospital Israelita Albert Einstein' named entity 'coinfection' named entity 'ethidium bromide' named entity 'human metapneumovirus' named entity 'rhinovirus' named entity 'chronic illnesses' named entity 'beta-actin' named entity 'day care' named entity 'virus infections' named entity 'SPSS' named entity 'RT-PCR' named entity 'coinfections' named entity 'cardiopathy' named entity 'human metapneumovirus' named entity 'saline' named entity 'Applied Biosystems' named entity 'steroids' named entity 'virus' named entity 'RSV' named entity 'atopy' named entity 'SPSS Inc.' named entity 'coinfections' named entity 'clinical examination' named entity 'urban area' named entity 'asthma' named entity 'risk factor' named entity 'Parainfluenza' named entity 'enterovirus' named entity 'prematurity' named entity 'coinfections' named entity 'cDNA' named entity 'enterovirus' named entity 'oxygen saturation' named entity 'odds ratio' named entity 'respiratory infections' named entity 'viruses' named entity 'Chicago' named entity 'bronchiolitis' named entity 'bronchiolitis' named entity '3/4' named entity 'rhinovirus' named entity 'young children' named entity 'confidence intervals' named entity 'RT-PCR' named entity 'enterovirus' named entity 'Fully informed' named entity 'genotype' named entity 'gastroesophageal reflux' named entity 'ICU'

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