About: Potential Effect of COVID-19 on Maternal and Infant Outcome: Lesson From SARS

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Potential Effect of COVID-19 on Maternal and Infant Outcome: Lesson From SARS
Creator	Wang, Yun Wang, Wang Solis-Moya, Arturo Arbo, Carlos, Sáenz Children's Hospital, Costa Duse, Marzia Han, Xiaoxue Herrera, National Li, Ruiman Rica, Antonio Wang, Yiliang Ye, Jiazhuo
source	Medline; PMC
abstract	The coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2, is highly infectious and its ongoing outbreak has been declared a global pandemic by the WHO. Pregnant women are susceptible to respiratory pathogens and the development of severe pneumonia, suggesting the urgent need to assess the potential maternal and infant outcome of pregnancy with COVID-19. The intrauterine vertical transmission potential of SARS-CoV-2 also remains controversial. Herein, we discuss the potential effect of COVID-19 on maternal and infant outcomes based on current studies, including those published in Chinese, in a total of 80 mothers with COVID-19 and 80 infants. We also comprehensively explored the mother-to-child transmission routes of SARS-CoV-2, in particular the route of intrauterine vertical transmission. Given SARS-CoV-2 is a sister to SARS-CoV, of the SARS-related coronavirus species, we made a comprehensive comparison between them to learn from experiences with SARS. Although there is no evidence supporting the intrauterine vertical transmission of SARS-CoV-2, our comprehensive analysis suggests that the adverse maternal and infant outcomes caused by COVID-19 cannot be underestimated. Further, we speculated that the inconsistency between nucleic acids and serological characteristics IgM to SARS-CoV-2 of infants' specimens may be caused by the disruption of the amniotic barrier by the inflammatory factors induced by SARS-CoV-2 infection. Our review is beneficial to understand the effect of SARS-CoV-2 on maternal and infant outcomes.
has issue date	2020-08-07(xsd:dateTime)
bibo:doi	10.3389/fped.2020.00511
bibo:pmid	32850564
has license	cc-by
sha1sum (hex)	9451b2cdfdd564ca27f202aa26c27e27e8a7c367
schema:url	https://doi.org/10.3389/fped.2020.00511
resource representing a document's title	Potential Effect of COVID-19 on Maternal and Infant Outcome: Lesson From SARS
has PubMed Central identifier	PMC7426626
has PubMed identifier	32850564
schema:publication	Front Pediatr
resource representing a document's body	covid:9451b2cdfdd564ca27f202aa26c27e27e8a7c367#body_text
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