About: Purpuric rash and fever among hospitalized children aged 0–18 years: Comparison between clinical, laboratory, therapeutic and outcome features of patients with bacterial versus viral etiology

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About: Purpuric rash and fever among hospitalized children aged 0–18 years: Comparison between clinical, laboratory, therapeutic and outcome features of patients with bacterial versus viral etiology Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Purpuric rash and fever among hospitalized children aged 0–18 years: Comparison between clinical, laboratory, therapeutic and outcome features of patients with bacterial versus viral etiology
Creator	Cavari, Yuval Fruchtman, Yariv Gawie-Rotman, Moran Hazan, Guy Lazar, Isaac Leibovitz, Eugene Ling, Eduard
Source	Elsevier; Medline; PMC
abstract	Background The evaluation of children with purpuric rash and fever (PRF) is controversial. Although many of them have viral infections, on occasion such patients may be infected with Neisseria meningitidis. We described all children aged 0–18 years with PRF in southern Israel during the period 2005 ̶ 2016 and compared their microbiologic, laboratory, clinical and outcome characteristics in relation to various etiologies of this syndrome. Methods Data were summarized from electronic patient and microbiology files. Viral diagnoses were made by serology and/or PCR. Results Sixty-nine children with PRF were admitted; 30 (43.48%), 9 (13.04%) and 30 (43.48%) had a syndrome of bacterial, viral or non-established etiology, respectively. N. meningitidis infection was diagnosed in 16/69 (23.19%) patients and in 16/30 (53.33%) patients with bacterial etiology; 14/30 (46.67%) patients suffered from a non-invasive bacterial disease (9 with Rickettsial disease). Adenovirus and Influenza B (3 and 2 cases, respectively) represented the most frequent etiologic agents among patients with viral etiology. More patients with PRF of bacterial etiology were older, of Bedouin ethnicity, looked ill on admission, had higher rates of meningitis and were treated more frequently with antibiotics compared with patients with non-bacterial PRF. Fatality rates among patients with bacterial, viral and non-established etiology were 5/30 (16.7%), 0% and 2/39 (5.1%). Conclusions Although PFR was uncommon, high rates of meningococcal infections were recorded in children with PRF, which was associated with high fatality rates. Rickettsial infections were frequent, emphasizing the need for a high index of suspicion for this disease in endemic geographic areas.
has issue date	2019-10-31(xsd:dateTime)
bibo:doi	10.1016/j.pedneo.2019.02.002
bibo:pmid	30922715
has license	els-covid
sha1sum (hex)	947224a63b916b8f6f70f9b9dffcdccd96988b06
schema:url	https://doi.org/10.1016/j.pedneo.2019.02.002
resource representing a document's title	Purpuric rash and fever among hospitalized children aged 0–18 years: Comparison between clinical, laboratory, therapeutic and outcome features of patients with bacterial versus viral etiology
has PubMed Central identifier	PMC7102717
has PubMed identifier	30922715
schema:publication	Pediatrics & Neonatology
resource representing a document's body	covid:947224a63b916b8f6f70f9b9dffcdccd96988b06#body_text
is schema:about of	named entity 'ill' named entity 'PRF' named entity 'areas' named entity 'Fatality' named entity 'patients' named entity 'meningococcal infections' named entity 'PFR' named entity 'MAY BE' named entity 'BACTERIAL' named entity 'SYNDROME' named entity 'SUSPICION' named entity 'PEDIATRICS' named entity 'PCR' named entity 'RICKETTSIAL INFECTIONS' named entity 'INFECTED' named entity 'ISRAEL' named entity 'TREATED' named entity 'VARIOUS' named entity 'SEROLOGY' named entity 'CLINICAL' named entity 'ELECTRONIC' named entity 'ETIOLOGIES' named entity 'VIRAL' named entity 'ADMITTED' named entity 'VIRAL AND' named entity 'LOOKED' named entity 'CHILDREN' named entity 'PFR' named entity 'GEOGRAPHIC AREAS' named entity 'NEED FOR' named entity 'FREQUENTLY' named entity 'MICROBIOLOGY' named entity 'UNCOMMON' named entity 'COMPARED' named entity 'BEDOUIN' named entity 'ENDEMIC' covid:arg/947224a63b916b8f6f70f9b9dffcdccd96988b06 named entity 'ARTICLE' named entity 'RECORDED' named entity 'PATIENT' named entity 'ESTABLISHED' named entity 'YEARS' named entity 'RELATION' named entity 'ETHNICITY' named entity 'NEONATOLOGY' named entity 'ANTIBIOTICS' named entity 'DISEASE' named entity 'VIRAL INFECTIONS' named entity 'HAVE' named entity 'CASES' named entity 'ETIOLOGY' named entity 'PATIENTS' named entity 'RICKETTSIAL DISEASE' named entity 'ADENOVIRUS' named entity 'DIAGNOSED' named entity 'BACKGROUND' named entity 'NON-' named entity 'HIGHER' named entity 'THEIR' named entity 'AGED' named entity '283' named entity 'RESULTS' named entity 'MENINGITIS' named entity 'CONCLUSIONS' named entity 'SUFFERED' named entity 'ORIGINAL' named entity 'PERIOD' named entity 'SIXTY-NINE' named entity 'DESCRIBED' named entity '60%' named entity 'EVALUATION' named entity 'INFECTION' named entity 'ILL' named entity 'ON ADMISSION' named entity 'MENINGOCOCCAL INFECTIONS'

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