About: Early CT features and temporal lung changes in COVID-19 pneumonia in Wuhan, China

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Early CT features and temporal lung changes in COVID-19 pneumonia in Wuhan, China
Creator	Ai, Tao Chen, Chong Xia, Liming Guan, Hanxiong Pan, Yueying Hu, Qiongjie Huang, Lu Sun, Ziyan
source	Elsevier; Medline; PMC
abstract	Abstract Purpose To analyse the high-resolution computed tomography (HRCT) early imaging features and the changing trend of coronavirus disease 2019 (COVID-19) pneumonia. Materials and Methods Forty-six patients with COVID-19 pneumonia who had an isolated lesion on the first positive CT were enrolled in this study. The following parameters were recorded for each lesion: sites, sizes, location (peripheral or central), attenuation (ground-glass opacity or consolidation), and other abnormalities (supply pulmonary artery dilation, air bronchogram, interstitial thickening, etc.). The follow-up CT images were compared with the previous CT scans, and the development of the lesions was evaluated. Results The lesions tended to be peripheral and subpleural. All the lesions exhibited ground-glass opacity with or without consolidation. A higher proportion of supply pulmonary artery dilation (89.13% [41/46]) and air bronchogram (69.57% [32/46]) were found. Other ﬁndings included thickening of the intralobular interstitium and a halo sign of ground glass around a solid nodule. Cavitation, calciﬁcation or lymphadelopathy were not observed. The reticular patterns were noted from the 14 days after symptoms onset in 7 of 20 patients (45%). At 22-31 days, the lesions were completely absorbed only in 2 of 7 patients(28.57%). Conclusion The typical early CT features of COVID-19 pneumonia are ground-glass opacity, and located peripheral or subpleural location, and with supply pulmonary artery dilation. Reticulation was evident after the 2nd week and persisted in half of patients evaluated in 4 weeks after the onset. Long-term follow-up is required to determine whether the reticulation represents irreversible ﬁbrosis.
has issue date	2020-04-19(xsd:dateTime)
bibo:doi	10.1016/j.ejrad.2020.109017
bibo:pmid	32387924
has license	els-covid
sha1sum (hex)	94b766fcebbb949573887fc3c8f7f87adb13fd61
schema:url	https://doi.org/10.1016/j.ejrad.2020.109017
resource representing a document's title	Early CT features and temporal lung changes in COVID-19 pneumonia in Wuhan, China
has PubMed Central identifier	PMC7166310
has PubMed identifier	32387924
schema:publication	Eur J Radiol
resource representing a document's body	covid:94b766fcebbb949573887fc3c8f7f87adb13fd61#body_text
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