About: Systemic Toxoplasmosis and Concurrent Porcine Circovirus-2 Infection in a Pig

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Systemic Toxoplasmosis and Concurrent Porcine Circovirus-2 Infection in a Pig
Creator	Baumgä, W Klein, S Wendt, M Wohlsein, P
Source	Elsevier; Medline; PMC
abstract	Summary Systemic toxoplasmosis and concurrent infection with porcine circovirus-2 (PCV-2) was diagnosed in a fattening pig. Clinical examination of the herd showed that up to 30% of the pigs of this weight group suffered from severe respiratory signs including sneezing and coughing, with a mortality rate of up to 5%. Gross necropsy examination revealed severe interstitial pneumonia and generalized lymphadenopathy. On microscopical examination there was necrotizing inflammation of the lung, adrenal glands and lymph nodes, associated with lymphoid depletion, cytoplasmic basophilic botryoid inclusion bodies and protozoal microorganisms. Infection with Toxoplasma gondii was confirmed by immunohistochemistry (IHC). Polymerase chain reaction analysis, in-situ hybridization and IHC confirmed systemic PCV-2 infection. These findings, associated with the respiratory signs and lesions in lymphoid tissues, are characteristic for post-weaning multisystemic wasting syndrome (PMWS). In this case, immunosuppression by PCV-2 may have triggered systemic toxoplasmosis, or immune stimulation caused by coinfection with T. gondii may have caused extensive replication of PCV-2.
has issue date	2010-04-30(xsd:dateTime)
bibo:doi	10.1016/j.jcpa.2009.08.155
bibo:pmid	19740479
has license	els-covid
sha1sum (hex)	95f53557f2720d662cbe99da98c2876391b0f001
schema:url	https://doi.org/10.1016/j.jcpa.2009.08.155
resource representing a document's title	Systemic Toxoplasmosis and Concurrent Porcine Circovirus-2 Infection in a Pig
has PubMed Central identifier	PMC7094381
has PubMed identifier	19740479
schema:publication	Journal of Comparative Pathology
resource representing a document's body	covid:95f53557f2720d662cbe99da98c2876391b0f001#body_text
is schema:about of	named entity 'severe' named entity 'triggered' named entity 'inflammation' named entity 'Porcine' named entity 'Systemic' named entity 'REVEALED' named entity 'CASE' named entity 'CONFIRMED BY' named entity 'LYMPHOID TISSUES' named entity 'INCLUDING' named entity 'SYSTEMIC' named entity 'PCV' named entity 'DIAGNOSED' named entity 'NECROPSY' named entity 'PORCINE CIRCOVIRUS-2' named entity 'NECROTIZING INFLAMMATION' named entity 'COINFECTION' named entity 'ASSOCIATED WITH' named entity 'GENERALIZED LYMPHADENOPATHY' named entity 'WASTING SYNDROME' named entity 'IHC' named entity 'CONCURRENT' named entity 'UP TO' named entity 'WEIGHT' named entity 'CAUSED BY' named entity 'SEVERE' named entity 'INTERSTITIAL PNEUMONIA' named entity 'FINDINGS' named entity 'MORTALITY RATE' named entity 'COUGHING' named entity 'IMMUNE' named entity '30%' named entity 'POLYMERASE CHAIN REACTION ANALYSIS' named entity 'TOXOPLASMOSIS' named entity 'LESIONS' named entity 'EXTENSIVE' named entity 'ADRENAL GLANDS' named entity 'CLINICAL EXAMINATION' named entity 'TOXOPLASMA GONDII' named entity 'INCLUSION BODIES' named entity 'LYMPHOID DEPLETION' named entity 'SIGNS' named entity 'IMMUNOHISTOCHEMISTRY' named entity 'CONFIRMED' named entity 'BASOPHILIC' named entity 'SNEEZING' named entity 'POST' named entity 'WEANING' named entity 'INFECTION' named entity 'SYSTEMIC' named entity 'TOXOPLASMOSIS' named entity 'PIG' named entity 'STIMULATION' named entity 'LUNG' named entity 'FATTENING PIG' named entity 'RESPIRATORY' named entity 'IMMUNOSUPPRESSION' named entity 'PIGS' named entity 'HERD' named entity 'REPLICATION' named entity 'MAY HAVE' named entity 'SUFFERED' named entity 'MICROORGANISMS' named entity 'EXAMINATION' named entity 'PROTOZOAL' named entity 'CYTOPLASMIC' named entity 'THESE' named entity 'LYMPH NODES' named entity 'GROSS' named entity 'INFECTION' named entity 'TRIGGERED' named entity 'GROUP' named entity 'PORCINE CIRCOVIRUS-2' named entity 'CONCURRENT' named entity 'CHARACTERISTIC' named entity 'HYBRIDIZATION' covid:arg/95f53557f2720d662cbe99da98c2876391b0f001 named entity 'stimulation'

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