About: Detection and Identification of Common Food-Borne Viruses with a Tiling Microarray

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Detection and Identification of Common Food-Borne Viruses with a Tiling Microarray
Creator	Patel, Isha Mammel, Mark Chen, Haifeng Jackson, Scott Kulka, Mike Goswami, Biswendu
Source	Medline; PMC
abstract	Microarray hybridization based identification of viral genotypes is increasingly assuming importance due to outbreaks of multiple pathogenic viruses affecting humans causing wide-spread morbidity and mortality. Surprisingly, microarray based identification of food-borne viruses, one of the largest groups of pathogenic viruses, causing more than 1.5 billion infections world-wide every year, has lagged behind. Cell-culture techniques are either unavailable or time consuming for routine application. Consequently, current detection methods for these pathogens largely depend on polymerase chain reaction (PCR) based techniques, generally requiring an investigator to preselect the target virus of interest. Here we describe the first attempt to use the microarray as an identification tool for these viruses. We have developed methodology to synthesize targets for virus identification without using PCR, making the process genuinely sequence independent. We show here that a tiling microarray can simultaneously detect and identify the genotype and strain of common food-borne viruses in a single experiment.
has issue date	2011-05-16(xsd:dateTime)
bibo:doi	10.2174/1874357901105010052
bibo:pmid	21660190
has license	cc-by-nc
sha1sum (hex)	9665e16e8fd0e3198298f64f70cc9180d1cea36a
schema:url	https://doi.org/10.2174/1874357901105010052
resource representing a document's title	Detection and Identification of Common Food-Borne Viruses with a Tiling Microarray
has PubMed Central identifier	PMC3109525
has PubMed identifier	21660190
schema:publication	Open Virol J
resource representing a document's body	covid:9665e16e8fd0e3198298f64f70cc9180d1cea36a#body_text
is schema:about of	named entity 'TILING MICROARRAY' named entity 'GENOTYPES' named entity 'AFFECTING' named entity 'METHODOLOGY' named entity 'THESE' named entity 'INDEPENDENT' named entity 'GROUPS' named entity 'USING' named entity 'HERE' named entity 'CAUSING' named entity 'DUE TO' named entity 'WORLD' named entity 'EITHER' named entity 'MORBIDITY AND MORTALITY' named entity 'GENOTYPE' named entity 'CELL' named entity 'PATHOGENS' named entity 'PATHOGENIC' named entity 'TARGETS' named entity 'polymerase' named entity 'hybridization' named entity 'identification' named entity 'developed' named entity 'BORNE' named entity 'VIRUS IDENTIFICATION' named entity 'PCR' named entity 'IDENTIFY' named entity 'CULTURE TECHNIQUES' named entity 'CONSUMING' named entity 'VIRUSES' named entity 'DETECTION' named entity 'COMMON' named entity 'DEPEND' named entity 'TIME' named entity 'CURRENT' named entity 'SPREAD' named entity 'TOOL' named entity 'FOOD' named entity 'FOOD' named entity 'IDENTIFICATION' named entity 'SYNTHESIZE' named entity 'EVERY YEAR' named entity 'HUMANS' named entity 'TARGET' named entity '1.5' named entity 'POLYMERASE CHAIN REACTION' named entity 'SIMULTANEOUSLY' named entity 'SEQUENCE' named entity 'HAVE' named entity 'BASED' named entity 'OF INTEREST' named entity 'MORE THAN' named entity 'TILING MICROARRAY' named entity 'HYBRIDIZATION' named entity 'EXPERIMENT' named entity 'MULTIPLE' named entity 'PROCESS' named entity 'TECHNIQUES' named entity 'VIRUSES' named entity 'DETECTION METHODS' named entity 'ONE OF' named entity 'ATTEMPT' named entity 'USE' named entity 'APPLICATION' named entity 'BORNE' named entity 'LARGEST' named entity 'VIRUS' named entity 'DESCRIBE' named entity 'MICROARRAY' named entity 'STRAIN' named entity 'GENERALLY' named entity 'SINGLE' named entity 'COMMON' named entity 'INVESTIGATOR' named entity 'VIRAL' named entity 'INFECTIONS'

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