About: Role of procalcitonin and C‐reactive protein in differentiation of mixed bacterial infection from 2009 H1N1 viral pneumonia

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About: Role of procalcitonin and C‐reactive protein in differentiation of mixed bacterial infection from 2009 H1N1 viral pneumonia Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Role of procalcitonin and C‐reactive protein in differentiation of mixed bacterial infection from 2009 H1N1 viral pneumonia
Creator	Kim, Sung-Han Koh, Younsuck Lim, Chae-Man Ahn, Shin Kim, Won Lim, Kyung Hong, Sangbum
Source	Medline; PMC
abstract	Please cite this paper as: Ahn et al. (2011) Role of procalcitonin and C‐reactive protein in differentiation of mixed bacterial infection from 2009 H1N1 viral pneumonia. Influenza and Other Respiratory Viruses 5(6), 398–403. Background Mixed bacterial infection is an important contributor to morbidity and mortality during influenza pandemics. We evaluated procalcitonin (PCT) and C‐reactive protein (CRP) in differentiating pneumonia caused by mixed bacterial and 2009 H1N1 influenza infection from 2009 H1N1 influenza infection alone. Methods Data were collected retrospectively over a 7‐month period during the 2009 H1N1 influenza pandemic. Patients visiting emergency department and diagnosed as community‐acquired pneumonia caused by 2009 H1N1 infection were included (n = 60). Results Mixed bacterial and viral infection pneumonia (n = 16) had significantly higher PCT and CRP levels than pneumonia caused by 2009 H1N1 influenza alone (n = 44, P = 0·019, 0·022 respectively). The sensitivity and specificity for detection of mixed bacterial infection pneumonia was 56% and 84% for PCT > 1·5 ng/ml, and 69% and 63% for CRP > 10 mg/dl. Using PCT and CRP in combination, the sensitivity and specificity were 50% and 93%, respectively. Conclusion Procalcitonin and CRP alone and their combination had a moderate ability to detect pneumonia of mixed bacterial infection during the 2009 H1N1 pandemic. Considering high specificity, combination of low CRP and PCT result may suggest that pneumonia is unlikely to be caused by mixed bacterial infection.
has issue date	2011-03-30(xsd:dateTime)
bibo:doi	10.1111/j.1750-2659.2011.00244.x
bibo:pmid	21668682
has license	no-cc
sha1sum (hex)	9741eab85f5510655de379d9e3c11f5bf0d2d560
schema:url	https://doi.org/10.1111/j.1750-2659.2011.00244.x
resource representing a document's title	Role of procalcitonin and C‐reactive protein in differentiation of mixed bacterial infection from 2009 H1N1 viral pneumonia
has PubMed Central identifier	PMC5780656
has PubMed identifier	21668682
schema:publication	Influenza Other Respir Viruses
resource representing a document's body	covid:9741eab85f5510655de379d9e3c11f5bf0d2d560#body_text
is schema:about of	named entity 'C-REACTIVE PROTEIN' named entity 'influenza' named entity 'INFLUENZA INFECTION' named entity 'INFLUENZA' named entity 'PANDEMICS' named entity 'MIXED' named entity 'PNEUMONIA' named entity 'H1N1 INFLUENZA' named entity 'MORBIDITY AND MORTALITY' named entity 'C-REACTIVE PROTEIN' named entity 'DIFFERENTIATING' named entity 'CONTRIBUTOR' named entity 'BACTERIAL INFECTION' named entity 'EVALUATED' named entity 'CAUSED BY' covid:arg/9741eab85f5510655de379d9e3c11f5bf0d2d560 named entity 'PROTEIN ' named entity 'BACKGROUND' named entity 'PROCALCITONIN' named entity 'ROLE' named entity 'VIRAL PNEUMONIA' named entity 'MIXED' named entity 'PROTEIN ' named entity 'H1N1' named entity 'IMPORTANT' named entity 'BACTERIAL INFECTION' named entity 'BACTERIAL' named entity 'DIFFERENTIATION' named entity 'PROCALCITONIN' named entity 'H1N1' named entity 'morbidity' named entity 'pneumonia' named entity '2009 H1N1 influenza' named entity '2009 H1N1 influenza' named entity 'influenza' named entity 'morbidity' named entity 'CRP' named entity 'infection' named entity '2009' named entity 'mixed infection' named entity 'retrospective studies' named entity 'PCR' named entity 'bacterial infection' named entity '95% confidence interval' named entity 'ROC curve' named entity 'chest X-rays' named entity 'pneumonia' named entity 'Staphylococcus aureus' named entity 'bacterial infection' named entity 'discrimination' named entity 'serum' named entity 'CRP' named entity 'France' named entity 'influenza infection' named entity 'antibiotic' named entity 'pneumonia' named entity 'legionella' named entity 'serum' named entity 'morbidity' named entity 'pneumonia' named entity 'bacterial resistance' named entity 'follow-up' named entity '2009 H1N1' named entity 'bacterial infection' named entity 'immunoassay' named entity 'pneumonia' named entity 'pathogenicity' named entity 'non-parametric' named entity 'influenza infection' named entity 'pneumonia' named entity 'pneumonia severity index' named entity 'Lyon' named entity 'WBC' named entity 'absolute neutrophil count' named entity 'radiographic'

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