About: Viral etiology of acute lower respiratory tract infections in hospitalized young children in Northern Taiwan

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Viral etiology of acute lower respiratory tract infections in hospitalized young children in Northern Taiwan
Creator	Chiu, Nan-Chang Chi, Hsin Huang, Fu-Yuan Sung, Chi-Chun Wang, Nai-Yu Weng, Li-Chuan Huang, Tsung-Ning
Source	Elsevier; Medline; PMC
abstract	BACKGROUND: Lower respiratory tract infections (LRTIs) comprise a great proportion of diagnoses among hospitalized children. This study identifies the viral pathogens causing LRTIs in young children and compares their clinical features and disease severity. METHODS: Children younger than 36 months old, hospitalized at a medical center in Northern Taiwan with acute bronchiolitis or pneumonia from April to December 2007, were prospectively enrolled. Nasopharyngeal aspiration fluid samples were sent for virus culture, for direct immunofluorescence test of respiratory syncytial virus (RSV), for rapid influenza viral identification, and for polymerase chain reaction of human metapneumovirus (hMPV), human boca virus (hBoV), and human corona virus. The clinical features and laboratory findings were recorded and analyzed. RESULTS: A total of 48 children were enrolled. RSV was the most common pathogen (41.7%), followed by hMPV (27.1%), hBoV, and enterovirus (both 6.3%). There were no significant differences in clinical presentation and disease severity between the RSV and hMPV groups. However, the hMPV group had a higher mixed infection rate (p = 0.038). Fourteen children had no identifiable viruses. Children with single, dual, and triple pathogens numbered 26, 7, and 1, respectively. The mixed infection rate reached 23.5% among 34 children with identifiable viruses. Children with a higher severity score had greater chance to develop asthma in the next 2 years (p = 0.042). CONCLUSION: RSV is the most common pathogen causing LRTIs in young children, followed by hMPV. The hMPV group had higher mixed infection rate than RSV group. hBoV does circulate in northern Taiwan.
has issue date	2011-01-18(xsd:dateTime)
bibo:doi	10.1016/j.jmii.2011.01.025
bibo:pmid	21524612
has license	no-cc
sha1sum (hex)	97e32ce65400ba4c756eaf62116533251440b414
schema:url	https://doi.org/10.1016/j.jmii.2011.01.025
resource representing a document's title	Viral etiology of acute lower respiratory tract infections in hospitalized young children in Northern Taiwan
has PubMed Central identifier	PMC7105033
has PubMed identifier	21524612
schema:publication	J Microbiol Immunol Infect
resource representing a document's body	covid:97e32ce65400ba4c756eaf62116533251440b414#body_text
is schema:about of	named entity 'YOUNG CHILDREN' named entity 'Taiwan' named entity 'VIRAL' named entity 'NORTHERN' named entity 'ETIOLOGY' named entity 'TAIWAN' named entity 'ACUTE' named entity 'LOWER RESPIRATORY TRACT INFECTIONS' named entity 'HOSPITALIZED' named entity 'etiology' named entity 'Viral' named entity 'wheezing' named entity 'coinfected' named entity 'viruses' named entity 'hMPV' named entity 'bronchiolitis' named entity 'subgroup analyses' named entity 'Statistical significance' named entity 'clinical characteristics' named entity 'RSV' named entity 'human bocavirus' named entity 'acute bronchiolitis' named entity 'RSV' named entity 'viruses' named entity 'fetal' named entity 'otitis' named entity 'RSV' named entity 'confidence interval' named entity 'fever' named entity 'wheezing' named entity 'laryngeal' named entity 'pathogen' named entity 'cyanosis' named entity 'gene' named entity 'clinical virology' named entity 'bronchiolitis' named entity 'Taiwan' named entity 'demographic data' named entity 'acute bronchiolitis' named entity 'oropharyngeal' named entity 'viruses' named entity 'viruses' named entity 'viruses' named entity 'lung fields' named entity 'infection' named entity 'Mann-Whitney U test' named entity 'virus' named entity 'bronchiolitis' named entity 'Atopic diseases' named entity 'tachypnea' named entity 'Viral' named entity 'virus' named entity 'Taipei' named entity 'adenovirus' named entity 'atopic diseases' named entity 'Italian' named entity 'chest Xray' named entity 'tracheitis' named entity 'viral infection' named entity 'viruses' named entity 'PCR' named entity 'PCR' named entity 'RNA' named entity 'RSV' named entity 'RSV' named entity 'rhinitis' named entity 'virus' named entity 'Acute bronchiolitis' named entity 'enterovirus' named entity 'Nucleic Acid' named entity 'acute bronchiolitis' named entity 'C-reactive protein' named entity 'viruses' named entity 'Taiwan' named entity 'acute bronchiolitis'

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