About: Impacts of triamcinolone acetonide on femoral head chondrocytic structures in lumbosacral plexus block

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About: Impacts of triamcinolone acetonide on femoral head chondrocytic structures in lumbosacral plexus block Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Impacts of triamcinolone acetonide on femoral head chondrocytic structures in lumbosacral plexus block
Creator	Cai, Fengjun Chen, Qian Gan, Yong Li, Xuesong Luo, Ping Meng, Fei Pan, Qi Wang, Dashou Wu, Qianming
topic	covid:98364308fd44bb4fb686480fb10c968e918715f1#this
Source	PMC
abstract	Objective: To investigate impacts of triamcinolone acetonide (TRI) on femoral head chondrocytic (FHC) structures when used for lumbosacral plexus block (LPB). Methods: A total of 32 6-month-old New Zealand white rabbits were selected (averagely weighing 2.75–3.25 kg) and added TRI into nerve block solution for LPB. The rabbit were randomly divided into four groups: group A1: 2.5 ml × 2 times, group A2 2.5 ml × 4 times, group B1 5 ml × 2 times, and group B2 5 ml × 4 times; the time interval among the injection was 5 days, and the structural changes of FHC were the observed using 50/100/200 light microscope; the modified Mankin pathological scoring was also performed for the evaluation. Results: There exhibited significant microscopic changes of FHC structures between the rabbits performed LPB and the normal rabbits, among which group B2 exhibited the most serious FHC damages, and the Mankin pathological score in group B2 was much higher than those in the other three groups, and the scores of the experimental group were higher than the control group. Conclusions: The addition of TRI in LPB can damage the FHC structures, and large-dose (5 ml/once) and long-course (four times) will result in more serious injuries.
has issue date	2017-04-21(xsd:dateTime)
bibo:doi	10.1016/j.jsps.2017.04.012
bibo:pmid	28579881
has license	cc-by-nc-nd
sha1sum (hex)	98364308fd44bb4fb686480fb10c968e918715f1
schema:url	https://doi.org/10.1016/j.jsps.2017.04.012
resource representing a document's title	Impacts of triamcinolone acetonide on femoral head chondrocytic structures in lumbosacral plexus block
has PubMed Central identifier	PMC5447409
has PubMed identifier	28579881
schema:publication	Saudi Pharm J
resource representing a document's body	covid:98364308fd44bb4fb686480fb10c968e918715f1#body_text
is http://vocab.deri.ie/void#inDataset of	proxy:http/ns.inria.fr/covid19/98364308fd44bb4fb686480fb10c968e918715f1
is schema:about of	named entity 'COURSE' named entity 'OBSERVED' named entity 'RABBITS' named entity 'GROUP A1' named entity 'FEMORAL HEAD' named entity '2.75' named entity 'SCORES' named entity 'CONTROL GROUP' named entity 'CHANGES' named entity 'INJURIES' named entity 'LUMBOSACRAL PLEXUS' named entity 'NORMAL' named entity 'RESULTS' named entity '2 TIMES' named entity 'SOLUTION' named entity 'MONTH' named entity 'DAMAGE' named entity 'LARGE' named entity 'MICROSCOPIC' named entity '50%' named entity '2.5' named entity 'nerve block' named entity 'microscopic' named entity 'lumbosacral plexus' named entity 'time' named entity 'DOSE' named entity 'DIVIDED' named entity 'GROUP A2' named entity 'FEMORAL HEAD' named entity 'OLD' named entity 'MUCH' named entity 'CONCLUSIONS' named entity 'NEW ZEALAND WHITE' named entity 'GROUPS' named entity 'OBJECTIVE' named entity 'TIMES' named entity 'LONG' named entity 'STRUCTURES' named entity 'BLOCK' named entity 'IMPACTS' named entity 'USING' named entity 'GROUP' named entity '4 TIMES' named entity 'SIGNIFICANT' named entity 'INJECTION' named entity 'RABBIT' named entity 'RESULT' named entity 'TRI' named entity 'ADDED' named entity 'SELECTED' named entity 'SCORING' named entity 'NERVE BLOCK' named entity 'EXPERIMENTAL GROUP' named entity 'TRIAMCINOLONE ACETONIDE' named entity 'PATHOLOGICAL' named entity 'USED' named entity 'DAYS' named entity 'HIGHER' named entity 'SCORE' named entity 'TRIAMCINOLONE ACETONIDE' named entity 'LUMBOSACRAL PLEXUS' named entity 'ADDITION' named entity 'EVALUATION' named entity 'PERFORMED' named entity 'TIME INTERVAL' named entity 'BLOCK' named entity 'MODIFIED' named entity 'WEIGHING' named entity 'TO INVESTIGATE' named entity 'FHC' named entity 'STRUCTURAL'

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