About: Advances in Visualization Tools for Phylogenomic and Phylodynamic Studies of Viral Diseases

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Advances in Visualization Tools for Phylogenomic and Phylodynamic Studies of Viral Diseases
Creator	Lemey, Philippe Baele, Guy Theys, Kristof Vandamme, Anne-Mieke Eden, John-Sebastian Eremin, Sergey Sintchenko, Vitali Baurain, Denis
source	Medline; PMC
abstract	Genomic and epidemiological monitoring have become an integral part of our response to emerging and ongoing epidemics of viral infectious diseases. Advances in high-throughput sequencing, including portable genomic sequencing at reduced costs and turnaround time, are paralleled by continuing developments in methodology to infer evolutionary histories (dynamics/patterns) and to identify factors driving viral spread in space and time. The traditionally static nature of visualizing phylogenetic trees that represent these evolutionary relationships/processes has also evolved, albeit perhaps at a slower rate. Advanced visualization tools with increased resolution assist in drawing conclusions from phylogenetic estimates and may even have potential to better inform public health and treatment decisions, but the design (and choice of what analyses are shown) is hindered by the complexity of information embedded within current phylogenetic models and the integration of available meta-data. In this review, we discuss visualization challenges for the interpretation and exploration of reconstructed histories of viral epidemics that arose from increasing volumes of sequence data and the wealth of additional data layers that can be integrated. We focus on solutions that address joint temporal and spatial visualization but also consider what the future may bring in terms of visualization and how this may become of value for the coming era of real-time digital pathogen surveillance, where actionable results and adequate intervention strategies need to be obtained within days.
has issue date	2019-08-02(xsd:dateTime)
bibo:doi	10.3389/fpubh.2019.00208
bibo:pmid	31428595
has license	cc-by
sha1sum (hex)	99d730ff4e80cd42f0304b9d80d7d0df0689888d
schema:url	https://doi.org/10.3389/fpubh.2019.00208
resource representing a document's title	Advances in Visualization Tools for Phylogenomic and Phylodynamic Studies of Viral Diseases
has PubMed Central identifier	PMC6688121
has PubMed identifier	31428595
schema:publication	Front Public Health
resource representing a document's body	covid:99d730ff4e80cd42f0304b9d80d7d0df0689888d#body_text
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