About: Clinical characteristics and changes of chest CT features in 307 patients with common COVID-19 pneumonia infected SARS-CoV-2: A multicenter study in Jiangsu, China

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About: Clinical characteristics and changes of chest CT features in 307 patients with common COVID-19 pneumonia infected SARS-CoV-2: A multicenter study in Jiangsu, China Goto Sponge NotDistinct Permalink

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Clinical characteristics and changes of chest CT features in 307 patients with common COVID-19 pneumonia infected SARS-CoV-2: A multicenter study in Jiangsu, China
Creator	Zhou, Ying Li, Yonggang Xu, Feng Xu, Chuanjun Author, Corresponding Li, Huang Dai, Hui Huang, Renjun Shang, Yalei Jiang, Fengli
Source	Elsevier; Medline; PMC
abstract	Abstract Objective The study was aimed to describe the clinical characteristics and evaluate the dynamic changes of chest CT features in the first week in the common type fo COVID-19 pneumonia patientsin Jiangsu Province. Methods 307 patients infected SARS-CoV-2 classified as common type were enrolled in the study. 628 chest CT scans were divided into three groups based on the time interval between symptoms and chest CT scan. The clinical characteristics were descriptively analyzed.The chest CT features were quantitatively evaluated. Mann-Whitney U test was used to test the differences in three groups and between men and women. Spearman rank correlation was used to test the association between the arterial blood gas(ABG) analysis results and chest CT scores. Results Fever (69.1%) and cough (62.8%) were common symptoms. 111(36.2%) patients were anorexia. GGO was the most common manifestation of COVID-19 pneumonia, which could be followed by consolidation and fibrosis. Lower lobe or subpleural region was the most common distribution form of lesion. More lung lobes involved in the third week. Total chest CT scores in the second week were higher than the first week. Fibrosis Scores increased in the second and third week. Total CT score, GGO score and fibrosis score of male patients were significantly higher than female in the second week. Male patients had higher consolidation score and fibrosis score than female in the third week. Total CT score and GGO score had weak to moderate correlation with arterial blood gas indices. Conclusion Changes in chest CT were difficult to assess quantitatively in the first third weeks. Male patients recovered slower than female in the second week. Although CT score had correlations with arterial blood gas indices, long-term follow-up of pulmonary function test is needed to determine the recovery of lung.
has issue date	2020-05-08(xsd:dateTime)
bibo:doi	10.1016/j.ijid.2020.05.006
bibo:pmid	32423888
has license	els-covid
sha1sum (hex)	99fdc3ffa49adf79a083f37c5c27228165141f9f
schema:url	https://doi.org/10.1016/j.ijid.2020.05.006
resource representing a document's title	Clinical characteristics and changes of chest CT features in 307 patients with common COVID-19 pneumonia infected SARS-CoV-2: A multicenter study in Jiangsu, China
has PubMed Central identifier	PMC7207103
has PubMed identifier	32423888
schema:publication	Int J Infect Dis
resource representing a document's body	covid:99fdc3ffa49adf79a083f37c5c27228165141f9f#body_text
is schema:about of	named entity 'SARS-CoV-2' named entity 'Author' named entity 'China' named entity 'Corresponding' named entity 'pneumonia' named entity 'chest CT' named entity 'chest CT' named entity 'Jiangsu' named entity 'China' named entity 'pneumonia' named entity 'CT scan' named entity 'CT scans' named entity 'Chest CT' named entity 'public health emergency of international concern' named entity '2020' named entity 'fibrosis' named entity 'pneumonia' named entity 'pneumonia' named entity 'GGO' named entity 'antiviral drugs' named entity 'lungs' named entity 'virus' named entity 'Anorexia' named entity 'lesion' named entity 'pneumonia' named entity 'runny nose' named entity 'fever' named entity 'arterial blood gas' named entity 'epidemic' named entity 'pneumonia' named entity 'fibrosis' named entity 'lymphadenopathy' named entity 'follow-up' named entity 'COVID' named entity '2020' named entity 'fraction of inspired oxygen' named entity 'correlation' named entity 'lung lobe' named entity 'COVID' named entity 'chest CT' named entity 'P-value' named entity 'pharyngeal' named entity 'highly contagious disease' named entity 'cough' named entity 'epidemiology' named entity 'COVID' named entity 'GGO' named entity '2020' named entity 'fibrosis' named entity 'China' named entity 'correlation' named entity '2020' named entity 'COVID-19' named entity 'rank correlation' named entity 'PaO2' named entity '2020' named entity 'symptom' named entity 'chest CT' named entity 'fibrosis' named entity 'China' named entity 'pulmonary function test' named entity 'chest CT' named entity 'GGO' named entity 'oxygen' named entity 'Coronavirus disease 2019' named entity 'lung lobes' named entity 'contact tracing' named entity 'laboratory test' named entity 'pneumonia' named entity 'laboratory test' named entity 'Fever' named entity 'GGO'

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