About: The Key Role of Genomics in Modern Vaccine and Drug Design for Emerging Infectious Diseases

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	The Key Role of Genomics in Modern Vaccine and Drug Design for Emerging Infectious Diseases
Creator	Rappuoli, Rino Dougan, Gordon Seib, Kate
Source	Medline; PMC
abstract	It can be argued that the arrival of the “genomics era” has significantly shifted the paradigm of vaccine and therapeutics development from microbiological to sequence-based approaches. Genome sequences provide a previously unattainable route to investigate the mechanisms that underpin pathogenesis. Genomics, transcriptomics, metabolomics, structural genomics, proteomics, and immunomics are being exploited to perfect the identification of targets, to design new vaccines and drugs, and to predict their effects in patients. Furthermore, human genomics and related studies are providing insights into aspects of host biology that are important in infectious disease. This ever-growing body of genomic data and new genome-based approaches will play a critical role in the future to enable timely development of vaccines and therapeutics to control emerging infectious diseases.
has issue date	2009-10-26(xsd:dateTime)
bibo:doi	10.1371/journal.pgen.1000612
bibo:pmid	19855822
has license	cc-by
sha1sum (hex)	9a1ed211481f2c4e15f48ec3f712e73901eb628a
schema:url	https://doi.org/10.1371/journal.pgen.1000612
resource representing a document's title	The Key Role of Genomics in Modern Vaccine and Drug Design for Emerging Infectious Diseases
has PubMed Central identifier	PMC2752168
has PubMed identifier	19855822
schema:publication	PLoS Genet
resource representing a document's body	covid:9a1ed211481f2c4e15f48ec3f712e73901eb628a#body_text
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